Browse our anti-IQGAP1 (IQGAP1) Antibodies

Full name:
anti-IQ Motif Containing GTPase Activating Protein 1 Antibodies (IQGAP1)
On www.antibodies-online.com are 103 IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) Antibodies from 21 different suppliers available. Additionally we are shipping IQGAP1 Kits (9) and and many more products for this protein. A total of 120 IQGAP1 products are currently listed.
Synonyms:
AA682088, D7Ertd237e, D7Ertd257e, HUMORFA01, mKIAA0051, p195, SAR1
list all antibodies Gene Name GeneID UniProt
IQGAP1 8826 P46940
IQGAP1 361598  
IQGAP1 29875 Q9JKF1

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Top referenced anti-IQGAP1 Antibodies

  1. Dog (Canine) Monoclonal IQGAP1 Primary Antibody for IF, IP - ABIN968063 : Hart, Callow, Souza, Polakis: IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. in The EMBO journal 1996 (PubMed)
    Show all 5 references for 968063

  2. Human Monoclonal IQGAP1 Primary Antibody for IF, WB - ABIN395438 : Liang, Fu, Zhang, Tang, Zhou, Wei, Chen: Honokiol inhibits HepG2 migration via down-regulation of IQGAP1 expression discovered by a quantitative pharmaceutical proteomic analysis. in Proteomics 2010 (PubMed)
    Show all 5 references for 395438

  3. Human Polyclonal IQGAP1 Primary Antibody for ELISA, WB - ABIN4327480 : Ren, Li, Sacks: IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling. in The Journal of biological chemistry 2008 (PubMed)

  4. Mouse (Murine) Polyclonal IQGAP1 Primary Antibody for ELISA, WB - ABIN314835 : Bi, Mancias, Goldberg: Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. in Developmental cell 2007 (PubMed)

  5. Human Polyclonal IQGAP1 Primary Antibody for ICC, IF - ABIN438475 : Sun, Kapuria, Peterson, Fang, Bornmann, Bartholomeusz, Talpaz, Donato: Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. in Blood 2011 (PubMed)

  6. Human Polyclonal IQGAP1 Primary Antibody for IF (cc), IF (p) - ABIN737796 : Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation. in Stem cells and development 2014 (PubMed)

More Antibodies against IQGAP1 Interaction Partners

Human IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) interaction partners

  1. findings suggest a novel role of IQGAP1 in insulin (show INS Antibodies)-regulated interaction between caveolae and cytoskeletal elements of the adipocyte, and that this is quelled in the diabetic state

  2. Alterated IQGAP1/Rho GTPase (show RACGAP1 Antibodies) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2 (show JAK2 Antibodies)/CALR (show CALR Antibodies) mutational status.

  3. our data suggest that IQ-domain GTPase-activating protein (show RASA1 Antibodies) 1 may promote the malignant phenotype of invasive ductal carcinoma via canonical Wnt (show WNT2 Antibodies) signaling, and it could be used as a potential prognostic biomarker for breast cancer patients.

  4. IQ domain of IQGAP1 is both necessary and sufficient for binding to ERK1 (show MAPK3 Antibodies) and ERK2 (show MAPK1 Antibodies), as well as to the MAPK (show MAPK1 Antibodies) kinases MEK1 (show MAP2K1 Antibodies) and MEK2 (show MAP2K2 Antibodies).

  5. Data indicate that the IQGAP1 N-terminal fragment spanning residues 1-191 (CHDF) binds to both F-actin and Ca(2 (show CA2 Antibodies)+)/calmodulin (show CALM1 Antibodies).

  6. These data were confirmed by phosphomimetic mutation of serine 1443 to glutamate within RGCT, which led to a significant reduction of IQGAP1 affinity for CDC42 and RAC1, clearly disclosing the critical role of RGCT for these interactions.

  7. These data reveal that IQGAP1 binds to YAP (show YAP1 Antibodies) and modulates its co-transcriptional function, suggesting that IQGAP1 participates in Hippo signaling.

  8. The results indicated that IQGAP1 was expressed at higher levels in glioma tissues compared with in normal brain tissues. IQGAP1siRNA significantly inhibited cell proliferation, and cell adhesion, migration and invasion.

  9. IQGAP1 protein is involved in normal cell physiology as well as oncologic processes.

  10. after AKT-mediated phosphorylation at serine 319, FOXO1 binds to IQGAP1, a hub for activation of the MAPK pathway, and impedes IQGAP1-dependent phosphorylation of ERK1/2 (pERK1/2).

Mouse (Murine) IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) interaction partners

  1. Data highlight a unique mechanism of formin (show FMN1 Antibodies) action in which mDia1 and INF2 (show INF2 Antibodies) function in series to stabilize MTs (show NEU2 Antibodies) and point to IQGAP1 as a scaffold that facilitates the activation of one formin (show FMN1 Antibodies) by another.

  2. Hectd1 (show HECTD1 Antibodies) regulates the protein level of IQGAP1 through ubiquitination.

  3. Loss of IQGAP1 results in impaired insulin (show INS Antibodies) signaling and glucose homeostasis in vivo.

  4. These data reveal that IQGAP1 binds to YAP (show YAP1 Antibodies) and modulates its co-transcriptional function, suggesting that IQGAP1 participates in Hippo signaling.

  5. IQGAP1 has a strong signaling relationship with Ras genes in induction of cancer and it is considered as a key gene for induction or suppression of the hepatocellular carcinoma.

  6. IQGAP1 has the potential to modulate airway contraction severity in acute asthma.

  7. we propose that IQGAP1 acts as a small GTPase (show RACGAP1 Antibodies) scaffolding platform within the small GTPase (show RACGAP1 Antibodies) network, and recruits and/or regulates small GTPases, small GTPase (show RACGAP1 Antibodies) regulators and effectors to orchestrate cell behavior

  8. This finding has new implications for involvement of IQGAP1 in cell polarization and migration events and potentially in cell cycle-associated nuclear envelope assembly/disassembly.

  9. IQGAP1 contributes to AngII-induced apoptosis of podocytes by interacting with the ERK1/2 (show MAPK1/3 Antibodies) signaling protein

  10. RSPO (show RSPO1 Antibodies)-LGR4 (show LGR4 Antibodies) not only induces the clearance of RNF43 (show RNF43 Antibodies)/ZNRF3 (show ZNRF3 Antibodies) to increase Wnt receptor levels but also recruits IQGAP1 into the Wnt (show WNT2 Antibodies) signaling complex.

IQGAP1 Antigen Profile

Antigen Summary

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Alternative names and synonyms associated with IQGAP1

  • IQ motif containing GTPase activating protein 1 (IQGAP1) antibody
  • IQ motif containing GTPase activating protein 1 (Iqgap1) antibody
  • AA682088 antibody
  • D7Ertd237e antibody
  • D7Ertd257e antibody
  • HUMORFA01 antibody
  • mKIAA0051 antibody
  • p195 antibody
  • SAR1 antibody

Protein level used designations for IQGAP1

RasGAP-like with IQ motifs , ras GTPase-activating-like protein IQGAP1 , Cdc42-Rac1 effector protein

GENE ID SPECIES
8826 Homo sapiens
361598 Rattus norvegicus
29875 Mus musculus
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