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|Antigen||Ras Homolog Gene Family, Member C (RHOC) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Caenorhabditis elegans (C. elegans), Fruit Fly (Drosophila melanogaster) Alternatives|
|Conjugate||This RHOC antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-RHOC AntibodyTarget Details RHOC Application Details Handling Images
|Specificity||RHOC antibody was raised against the N terminal of RHOC|
|Immunogen||RHOC antibody was raised using the N terminal of RHOC corresponding to a region with amino acids VPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCF|
Target Details RHOCProduct Details anti-RHOC Antibody Application Details Handling Images back to top
|Alternative Name||RHOC (RHOC Antibody Abstract)|
|Background||RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.|
|Molecular Weight||22 kDa (MW of target protein)|
|Pathways||WNT Signaling, Cell-Cell Junction Organization|
Application DetailsProduct Details anti-RHOC Antibody Target Details RHOC Handling Images back to top
WB: 1 µg/mL
Optimal conditions should be determined by the investigator.
RHOC Blocking Peptide, catalog no. 33R-9740, is also available for use as a blocking control in assays to test for specificity of this RHOC antibody
|Restrictions||For Research Use only|
HandlingProduct Details anti-RHOC Antibody Target Details RHOC Application Details Images back to top
|Reconstitution||Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RHOC antibody in PBS|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.|
ImagesProduct Details anti-RHOC Antibody Target Details RHOC Application Details Handling back to top