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anti-Fruit Fly (Drosophila melanogaster) RHOC antibody for Immunohistochemistry

Recommended RHOC Antibody (supplied by: Log in to see )

Antigen
Ras Homolog Gene Family, Member C (RHOC) Antibodies
  • AI324259
  • Arh9
  • ARH9
  • Arhc
  • ARHC
  • CRHOC
  • H9
  • LOC100221682
  • RHOH9
Epitope
N-Term
25
15
10
4
3
3
2
1
1
1
Reactivity
Caenorhabditis elegans (C. elegans), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
66
14
12
2
2
2
1
Host
Rabbit
40
27
Clonality
Polyclonal
Conjugate
This RHOC antibody is un-conjugated
3
3
3
3
3
3
Application
Immunohistochemistry (IHC), Western Blotting (WB)
61
35
24
8
7
3
1
1
Supplier
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Catalog No. ABIN2786344
$ 289.00
Plus shipping costs $45.00

Top referenced anti-RHOC antibody for Immunohistochemistry

Similar anti-RHOC Antibodies

Application / Reactivity Human Caenorhabditis elegans (C. elegans) Dog (Canine) Fruit Fly (Drosophila melanogaster) Mouse (Murine) Rat (Rattus) Xenopus laevis
Western Blotting (WB) 61 Antibodies 3 Antibodies 3 Antibodies 3 Antibodies 14 Antibodies 12 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies 3 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 1 Antibodies 1 Antibodies 25 Antibodies 6 Antibodies 5 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies 1 Antibodies

General

Antigen Ras Homolog Gene Family, Member C (RHOC) Antibodies
Epitope N-Term
(25), (15), (10), (4), (3), (3), (2), (1), (1), (1)
Reactivity Caenorhabditis elegans (C. elegans), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(66), (14), (12), (2), (2), (2), (1)
Host Rabbit
(40), (27)
Clonality
Polyclonal
Conjugate This RHOC antibody is un-conjugated
(3), (3), (3), (3), (3), (3)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(61), (35), (24), (8), (7), (3), (1), (1)
Pubmed 1 reference available
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Product Details anti-RHOC Antibody

Target Details RHOC Application Details Handling References for anti-RHOC Antibody (ABIN2786344) Images
Blocking Peptide Blocking peptide for this product available: ABIN982963
Sequence VPTVFENYIA DIEVDGKQVE LALWDTAGQE DYDRLRPLSY PDTDVILMCF
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Human : 100 %, Mouse : 100 %
Characteristics This is a rabbit polyclonal antibody against RHOC. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RHOC

Target Details RHOC

Product Details anti-RHOC Antibody Application Details Handling References for anti-RHOC Antibody (ABIN2786344) Images back to top
Antigen
Alternative Name RHOC (RHOC Antibody Abstract)
Background RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Molecular Weight 22 kDa
Gene ID 389
NCBI Accession NM_175744, NP_786886
UniProt P08134
Research Area Cancer
Pathways WNT Signaling

Application Details

Product Details anti-RHOC Antibody Target Details RHOC Handling References for anti-RHOC Antibody (ABIN2786344) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 193 AA

Restrictions For Research Use only

Handling

Product Details anti-RHOC Antibody Target Details RHOC Application Details References for anti-RHOC Antibody (ABIN2786344) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-RHOC Antibody (ABIN2786344)

Product Details anti-RHOC Antibody Target Details RHOC Application Details Handling Images back to top
Product cited in:

Sousa, Espreafico: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." in: BMC cancer, Vol. 8, pp. 19, 2008

Images

Product Details anti-RHOC Antibody Target Details RHOC Application Details Handling References for anti-RHOC Antibody (ABIN2786344) back to top
Supplier Images
Western Blotting (WB) image for anti-RHOC antibody (Ras Homolog Gene Family, Member C) (N-Term) (ABIN2786344) WB Suggested Anti-RHOC Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...