anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1) Antibodies

ASAP1 encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. Additionally we are shipping ASAP1 Kits (3) and ASAP1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASAP1 13196 Q9QWY8
ASAP1 50807 Q9ULH1
ASAP1 314961 Q1AAU6
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Top anti-ASAP1 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rabbit Un-conjugated IHC, ELISA, WB 1.09 mg/ml (by UV absorbance at 280 nm) 100 μg 5 to 7 Days
$598.50
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg 5 to 7 Days
$598.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ASAP1 using Jurkat whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Cow Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$632.50
Details
Cow Rabbit Un-conjugated EIA, IF, WB   0.1 mg 4 to 8 Days
$632.50
Details
Mouse Rabbit Un-conjugated WB 100 μg 11 to 14 Days
$507.83
Details
Chicken Rabbit Un-conjugated ICC, IF, ELISA, WB 100 μg 11 to 14 Days
$639.83
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to DDEF1 on HeLa cell. [antibody concentration 10 ug/ml] DDEF1 monoclonal antibody (M01), clone 2G7 Western Blot analysis of DDEF1 expression in IMR-32 . 100 μg 11 to 12 Days
$440.00
Details
Mouse Rabbit Un-conjugated WB Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB MDA-MB-231 Cell lysates probed with ASAP1 Polyclonal Antibody, unconjugated (bs-4091R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. Paraformaldehyde-fixed, paraffin embedded Mouse small intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with ASAP1 Polyclonal Antibody, Unconjugated (bs-4091R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL 3 to 7 Days
$317.90
Details

Top referenced anti-ASAP1 Antibodies

  1. Cow (Bovine) Polyclonal ASAP1 Primary Antibody for IF, ELISA - ABIN538233 : Liu, Loijens, Martin, Karginov, Parsons: The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. in Molecular biology of the cell 2002 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal ASAP1 Primary Antibody for IF, IHC (p) - ABIN538232 : Kruljac-Letunic, Moelleken, Kallin, Wieland, Blaukat: The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Polyclonal ASAP1 Primary Antibody for IHC, ELISA - ABIN129669 : Bender, Stritt, Nurden, van Eeuwijk, Zieger, Kentouche, Schulze, Morbach, Stegner, Heinze, Heinze, Dütting, Gupta, Witke, Falet, Fischer, Hartwig, Nieswandt: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. in Nature communications 2015 (PubMed)

  4. Mouse (Murine) Polyclonal ASAP1 Primary Antibody for ELISA, WB - ABIN129670 : Sato, Zhao, Imai, Simister, Feller, Trackman, Kirsch, Sonenshein: Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. in PLoS ONE 2013 (PubMed)

  5. Human Polyclonal ASAP1 Primary Antibody for ICC, IF - ABIN4281768 : Schreiber, Saraswati, Harkins, Gruber, Cremers, Thiele, Rothley, Plaumann, Korn, Armant, Augustin, Sleeman: Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling. in PLoS genetics 2019 (PubMed)

More Antibodies against ASAP1 Interaction Partners

Mouse (Murine) ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1) interaction partners

  1. these data indicated that ribosomal protein S19 polymer plays the roles in the early erythroblast differentiation of C57BL/6J mouse spleen

  2. results support the hypothesis that ASAP1 is a positive regulator of NM2A.

  3. we demonstrate that Prox1 and Asap1 behave as negative regulators of mammary stem/progenitor function. Both of these genes have also been implicated in oncogenesis.

  4. ASAP1 is a scaffold bringing together the proteins needed for transport to the cilia including the GTP-binding protein Arf4 & the 2 G proteins of the Rab family--Rab11 & Rab8--linked by the Rab8 guanine nucleotide exchange factor Rabin8.

  5. ASAP1 was suggested to negatively regulate lipopolysaccharide (LPS)-induced proinflammatory mediators production through down-regulating LPS signaling

  6. DEF-1 alters cell motility through the deactivation of ARF1. In contrast, the inhibition of cell spreading by DEF-1 was not dependent on GAP activity, indicating that spreading and motility are altered by DEF-1 through different pathways.

  7. association with focal adhesion kinases contributes to the process of focal adhesion assembly

  8. inhibited by tyrosine kinase Pyk2, which also regulates Arf1

  9. Overexpression of ASAP1 inhibits cell spreading and alters paxillin localization to adhesions.

  10. ASAP1 may function as a coincidence detector of simultaneous protein association through the ASAP1 SH3 domain and phosphorylation by Src.

  11. ASAP3 functions nonredundantly with ASAP1 to control cell movement and may have a role in cancer cell invasion.

Human ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1) interaction partners

  1. rs4733781 A allele of ASAP1 is associated with a decreased risk of tuberculosis in Han Chinese.

  2. Histone modifications of certain miRNA loci, such as the miR-183-96-182 cistron, are different between epithelial cells and non-epithelial cells

  3. AMAP1 mediated CCL18-induce activation of NF-kappaB and promoted breast cancer metastasis.

  4. Results indicate that monocyte differentiation involves enhancement of IRES activity, by which protein levels of AMAP1 are primarily upregulated.

  5. Less differentiated embryonal and undifferentiated small hepatoblastoma cells progressively lose EGFR and ASAP1 expression. This trend is exaggerated in unresectable, locally invasive or metastatic tumors.

  6. eIF5B promoted hepatocellular carcinoma cell proliferation and migration in vitro and in vivo partly through increasing ASAP1 expression.

  7. results, specifically, the absence of associations of polymorphisms of ASAP1 with tuberculosis (TB) risk, suggest that ASAP1 may not be a susceptibility gene for TB in Western Chinese Han and Tibetan population

  8. results support the hypothesis that ASAP1 is a positive regulator of NM2A.

  9. Rab11-FIP3 coordinates the interactions of ASAP1 and Rab11a with Rabin8.

  10. The activation of NF-kappaB induced translocation of AMAP1 to cytoplasm from cell membrane and nucleus, which resulted in augmented interaction of AMAP1 and IKKbeta

  11. High ASAP1 expression, that was reduced after Mycobacterium tuberculosis infection, and rs10956514, are associated with the level of reduction of ASAP1 expression.

  12. ASAP1 appears to contribute to the malignant mechanism of LSCC and may represent a significant prognostic marker for laryngeal squamous cell carcinoma patients.

  13. results indicated that elevated expression of ASAP1 plays an important role in the progression and metastasis of ovarian cancer

  14. Data show that co-overexpression of GEP100 and AMAP1 (ASAP1) correlates with rapidity of the local recurrence.

  15. found that AMAP1 had the ability to bind directly to PRKD2 and hence to make a complex with the cytoplasmic tail of the beta1 subunit

  16. Data suggest that GEP100-Arf6-AMAP1-cortactin pathway, activated by VEGFR2, appears to be common in angiogenesis and cancer invasion and metastasis, and provides their new therapeutic targets.

  17. GEFH1 was identified as binding partner for the BAR domain of ASAP1.GEFH1 is a negative regulator of podosomes.

  18. ASAP1 can contribute to the dissemination of a variety of tumor types and represent a potential target for cancer therapy.

  19. DEF-1 alters cell motility through the deactivation of ARF1. In contrast, the inhibition of cell spreading by DEF-1 was not dependent on GAP activity, indicating that spreading and motility are altered by DEF-1 through different pathways.

  20. These results suggest that POB1 interacts with PAG2 through its proline-rich motif, thereby regulating cell migration (PAG2).

ASAP1 Antigen Profile

Protein Summary

This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ASAP1

  • ArfGAP with SH3 domain, ankyrin repeat and PH domain1 (Asap1) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1) antibody
  • toxic extracellular endopeptidase (asaP1) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (Asap1) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (asap1) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog (asap1.L) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a (asap1a) antibody
  • AMAP1 antibody
  • Asap1 antibody
  • AV239055 antibody
  • CENTB4 antibody
  • ddef1 antibody
  • DEF-1 antibody
  • mKIAA1249 antibody
  • PAG2 antibody
  • PAP antibody
  • s19 antibody
  • si:ch211-160i2.3 antibody
  • ZG14P antibody

Protein level used designations for ASAP1

130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein , 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein , ADP-ribosylation factor-directed GTPase-activating protein 1 , ARF GTPase-activating protein 1 , PIP2-dependent ARF1 GAP , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 , development and differentiation-enhancing factor 1 , DEF-1 , centaurin, beta 4 , development and differentiation enhancing factor 1 , differentiation-enhancing factor 1 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like , ArfGAP with SH3 domain, ankyrin repeat and PH domain1 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a , arfGAP with SH3 domain, ankyrin repeat and PH domain 1a

GENE ID SPECIES
13196 Mus musculus
50807 Homo sapiens
4998702 Aeromonas salmonicida subsp. salmonicida A449
314961 Rattus norvegicus
327705 Bos taurus
695681 Macaca mulatta
100036721 Xenopus (Silurana) tropicalis
100076691 Ornithorhynchus anatinus
428385 Gallus gallus
464399 Pan troglodytes
482044 Canis lupus familiaris
100407033 Callithrix jacchus
100484741 Ailuropoda melanoleuca
100581096 Nomascus leucogenys
100722888 Cavia porcellus
108718606 Xenopus laevis
100170829 Danio rerio
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