Caspase Recruitment Domain Family, Member 10 Proteins (CARD10)

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. Additionally we are shipping CARD10 Antibodies (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CARD10 CARD10 315120  
CARD10 29775 Q9BWT7
CARD10 105844 P58660
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Top CARD10 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details

CARD10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Caspase Recruitment Domain Family, Member 10 (CARD10) Interaction Partners

Human Caspase Recruitment Domain Family, Member 10 (CARD10) interaction partners

  1. The results suggest that the involvement of CARMA3 in DNA damage-induced NF-kappaB is through the recruitment of TRAF6.

  2. Card10 polymorphisms may not be linked with psoriasis vulgaris in the southern Han Chinese population.

  3. Data indicate no association between caspase recruitment domain family, member 10 protein (CARD10) polymorphism rs6000782 and type 1 autoimmune hepatitis (AIH) in a Japanese population.

  4. Findings indicate that CARMA3 may suppress the activation of the P38 MAPK signaling pathway to regulate invasion, migration and apoptosis of lung cancer cells by activating NF-small ka, CyrillicB (P65) in the nucleus.

  5. miR-24 inhibited cell proliferation, invasion and epithelial to mesenchymal transition in bladder cancer cells by downregulation of CARMA3

  6. The study identified the DEP domain-containing protein DEPDC7 as cellular binding partner of CARMA2 and CARMA3 proteins.

  7. A novel mechanism of CARMA3 in lung cancer stemness and metastasis through the negative regulation of NME2 was identified.

  8. CARMA3 regulates the ovarian cancer cell proliferation, cell cycle progression, and chemoresistance.

  9. CARMA3 is overexpressed in pancreatic cancer and regulates malignant cell growth, invasion, and NF-kappaB signaling, which was dependent on its association with Bcl10.

  10. CARMA3 is overexpressed in bladder cancer and regulates malignant cell growth and NF-kappaB signaling.

  11. Genetic variation within PARP1 and CARD10 was associated with rate of hippocampal neurodegeneration in APOE e3/e3 patients.

  12. CARD10 may be involved in hepatic carcinogenesis associated with hepatitis C in Egyptian patients.

  13. overexpression of CARMA3 in human glioma and its correlation with tumor grade.

  14. Data show that CARMA3 may serve as a novel and prognostic marker for renal cell carcinoma (RCC) and play a role during the development and progression of the disease.

  15. CARMA3 facilitates proliferation and inhibits apoptosis through nuclear factor-kappaB signaling.

  16. miR-146a expression is up-regulated in a majority of gastric cancers where it targets CARD10 and COPS8, inhibiting GPCR-mediated activation of NF-kappaB.

  17. this study found that CARMA3 is overexpressed in colon cancers and contributes to malignant cell growth by facilitating cell cycle progression through NF-kappaB mediated upregulation of cyclin D1.

  18. The overexpression of CARMA3 was significantly correlated with TNM stage (P = 0.022) and tumor status (P = 0.013).

  19. Polymorphisms of ATOH7, TGFBR3 and CARD10 influence the size of optic disc area.

  20. Data show that CARMA3 and Bcl10 contributed to several characteristics of EGFR-associated malignancy, including proliferation, survival, migration, and invasion.

Mouse (Murine) Caspase Recruitment Domain Family, Member 10 (CARD10) interaction partners

  1. CARMA3 is gradually turned over following vesicular stomatitis virus infection, which may serve as a mechanism to turn off NF-kB activation, it releases MAVS to form functional aggregates to induce interferon regulatory factor 3 activation.

  2. CARMA3 is critical for the initiation of allergic airway inflammation.

  3. Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3.Bcl10.MALT1 signalosome

  4. the type 1 receptor for angiotensin II utilizes the CARMA3-Bcl10-MALT1 signalosome for activation of NF-kappaB in endothelial and vascular smooth muscle cells, thereby inducing pro-inflammatory signals within the vasculature

  5. CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in hepatocytes.

  6. Together, results provide the genetic evidence that CARMA3 is required for G protein-coupled receptor-induced NF-kappaB activation.

  7. Data demonstrate that lysophosphatidic acid stimulates thymic stromal lymphopoietin and CCL20 expression in bronchial epithelial cells via CARMA3-mediated NF-kappaB activation.

  8. components of the CBM complex, Carma3, Bcl10, and Malt1 are key mediators of the CXCL8/IL8-induced NFkappaB activation and VEGF up-regulation.

CARD10 Protein Profile

Protein Summary

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB\; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001

Gene names and symbols associated with CARD10

  • caspase recruitment domain family, member 10 (Card10)
  • caspase recruitment domain family member 10 (CARD10)
  • AI449026 protein
  • Bimp1 protein
  • CARD10 protein
  • Carma3 protein

Protein level used designations for CARD10

caspase recruitment domain-containing protein 10 , caspase recruitment domain family, member 10 , caspase recruitment domain protein 10 , caspase recruitment domain-containing protein 10-like , Bcl10 binding protein and activator of NFKB , CARD-containing MAGUK 3 protein , CARD-containing MAGUK protein 3 , carma 3 , bcl10-interacting MAGUK protein 1

GENE ID SPECIES
315120 Rattus norvegicus
481268 Canis lupus familiaris
418041 Gallus gallus
458812 Pan troglodytes
535188 Bos taurus
100428402 Macaca mulatta
100478802 Ailuropoda melanoleuca
100079406 Ornithorhynchus anatinus
100219536 Taeniopygia guttata
100025552 Monodelphis domestica
100539234 Meleagris gallopavo
29775 Homo sapiens
105844 Mus musculus
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