anti-Charged Multivesicular Body Protein 4B (CHMP4B) Antibodies

CHMP4B encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. Additionally we are shipping CHMP4B Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHMP4B 128866 Q9H444
CHMP4B 75608 Q9D8B3
CHMP4B 100359642  
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Top anti-CHMP4B Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate WB Suggested Anti-CHMP4B  Antibody Titration: 0.2-1 µg/mL  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-CHMP4B/CHMP4C Polyclonal Antibody, Unconjugated (ABIN872575) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CHMP4B Antibody (N-term) (ABIN653481) in SK-BR-3 cell line lysates (35 µg/lane).CHMP4B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CHMP4B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse heart tissue, using CHMP4B antibody. ABIN6273100 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Bat Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated WB CHMP4B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$510.36
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

Top referenced anti-CHMP4B Antibodies

  1. Cow (Bovine) Polyclonal CHMP4B Primary Antibody for WB - ABIN2785348 : Bodon, Chassefeyre, Pernet-Gallay, Martinelli, Effantin, Hulsik, Belly, Goldberg, Chatellard-Causse, Blot, Schoehn, Weissenhorn, Sadoul: Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane. in The Journal of biological chemistry 2011 (PubMed)

  2. Human Polyclonal CHMP4B Primary Antibody for FACS, IHC (p) - ABIN653481 : Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma. in Tumour biology 2015 (PubMed)

More Antibodies against CHMP4B Interaction Partners

Human Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. Data (including data from studies using transgenic mice) suggest that the process leading to microparticle release from cardiac myocytes involves recruitment of CHMP4B protein to the forming microparticle membrane which also contains cBIN1; plasma cBIN1 is reduced in patients with heart failure as compared to control subjects. (CHMP4B = charged multivesicular body protein 4B; cBIN1 = cardiac bridging integrator 1)

  2. homologous domain of human Bro1 domain-containing proteins, Alix and Brox, binds CHMP4B but not STAM2, despite their high structural similarity

  3. The ESCRT-III subunit CHMP4B is a key effector in abscission, whereas its paralogue, CHMP4C, is a component in the abscission checkpoint that delays abscission until chromatin is cleared from the intercellular bridge.

  4. our results implied that CHMP4B could be a promising prognostic biomarker as well as a potential therapeutic target of HCC.

  5. CHMP4B, through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

  6. CHMP4B interacts directly with CC2D1A and CC2D1B with nanomolar affinity by forming a 1:1 complex.

  7. CC2D1A interaction with CHMP4B/4A blocks HIV-1 budding.

  8. hSnf7-1 and hSnf7-2 are preferentially associated with CHMP2A and CHMP2B, respectively, and regulate the turnover of distinct transmembrane cargos such as neurotransmitter receptors in human neurons.

  9. CHMP4b and Alix participate in formation of multivesicular bodies by cooperating with SKD1

  10. ALIX can have a dramatic effect on HIV-1 release by binding at the CHMP4B site; the ability to use ALIX may allow HIV-1 to replicate in cells that express only low levels of Tsg101

  11. These data provide the first evidence that CHMP4B plays a vital role the maintenance of lens transparency.

  12. Results suggest that efficient interaction between CHMP4s and Brox requires Brox farnesylation.

  13. Study demonstrates that CHMP4A and CHMP4B proteins form novel membrane-attached filaments that can promote or stabilize negative curvature and outward budding.

  14. The Bro1 domain of ALIX binds specifically to C-terminal residues of the human CHMP4B.

  15. The CHMP4b- and Src-docking sites in the Bro1 domain are autoinhibited in the native state of Alix.

Mouse (Murine) Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. CHMP4B, through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

CHMP4B Antigen Profile

Protein Summary

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

Gene names and symbols associated with CHMP4B

  • charged multivesicular body protein 4B (CHMP4B) antibody
  • charged multivesicular body protein 4B (Chmp4b) antibody
  • charged multivesicular body protein 4Ba (chmp4ba) antibody
  • charged multivesicular body protein 4B L homeolog (chmp4b.L) antibody
  • charged multivesicular body protein 4Bb (chmp4bb) antibody
  • 2010012F05Rik antibody
  • c20orf178 antibody
  • C76846 antibody
  • CHMP4A antibody
  • chmp4b antibody
  • chmp4b.S antibody
  • CHMP4c antibody
  • CTPP3 antibody
  • CTRCT31 antibody
  • dJ553F4.4 antibody
  • RGD1309846 antibody
  • RGD1565889 antibody
  • Shax1 antibody
  • SNF7 antibody
  • Snf7-2 antibody
  • Vps32-2 antibody
  • VPS32B antibody
  • wu:fc96b02 antibody
  • zgc:55566 antibody

Protein level used designations for CHMP4B

SNF7 homolog associated with Alix 1 , Snf7 homologue associated with Alix 1 , charged multivesicular body protein 4b , chromatin modifying protein 4B , chromatin-modifying protein 4b , hSnf7-2 , hVps32-2 , vacuolar protein sorting-associated protein 32-2 , vacuolar protein-sorting-associated protein 32-2 , CHMP4b , Chromatin-modifying protein 4b , charged multivesicular body protein 4B S homeolog , CHMP4c , Chromatin-modifying protein 4c , charged multivesicular body protein 4B , charged multivesicular body protein 4c , chromatin-modifying protein 4c

GENE ID SPECIES
128866 Homo sapiens
75608 Mus musculus
419150 Gallus gallus
393164 Danio rerio
100359642 Rattus norvegicus
495125 Xenopus laevis
100714567 Cavia porcellus
406766 Danio rerio
485842 Canis lupus familiaris
616164 Bos taurus
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