anti-Charged Multivesicular Body Protein 4B (CHMP4B) Antibodies

CHMP4B encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. Additionally we are shipping CHMP4B Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHMP4B 128866 Q9H444
CHMP4B 75608 Q9D8B3
CHMP4B 100359642  
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Top anti-CHMP4B Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-CHMP4B Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>THP-1 cell lysate WB Suggested Anti-CHMP4B <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CHMP4B Antibody (N-term) (ABIN653481) in SK-BR-3 cell line lysates (35 µg/lane).CHMP4B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CHMP4B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-CHMP4B/CHMP4C Polyclonal Antibody, Unconjugated (ABIN872575) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

CHMP4B Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CHMP4B Antibodies

  1. Human Polyclonal CHMP4B Primary Antibody for FACS, IHC (p) - ABIN653481 : Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma. in Tumour biology 2015 (PubMed)

  2. Cow (Bovine) Polyclonal CHMP4B Primary Antibody for WB - ABIN2785348 : Bodon, Chassefeyre, Pernet-Gallay, Martinelli, Effantin, Hulsik, Belly, Goldberg, Chatellard-Causse, Blot, Schoehn, Weissenhorn, Sadoul: Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against CHMP4B Interaction Partners

Human Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. Data (including data from studies using transgenic mice) suggest that the process leading to microparticle release from cardiac myocytes involves recruitment of CHMP4B (show CHMP4A Antibodies) protein to the forming microparticle membrane which also contains cBIN1; plasma cBIN1 is reduced in patients with heart failure as compared to control subjects. (CHMP4B (show CHMP4A Antibodies) = charged multivesicular body protein 4B; cBIN1 = cardiac bridging integrator 1 (show BIN1 Antibodies))

  2. homologous domain of human Bro1 (show HMGCR Antibodies) domain-containing proteins, Alix (show PDCD6IP Antibodies) and Brox, binds CHMP4B (show CHMP4A Antibodies) but not STAM2 (show STAM2 Antibodies), despite their high structural similarity

  3. The ESCRT-III subunit CHMP4B (show CHMP4A Antibodies) is a key effector in abscission, whereas its paralogue, CHMP4C (show CHMP4C Antibodies), is a component in the abscission checkpoint that delays abscission until chromatin is cleared from the intercellular bridge.

  4. our results implied that CHMP4B (show CHMP4A Antibodies) could be a promising prognostic biomarker as well as a potential therapeutic target of HCC (show FAM126A Antibodies).

  5. CHMP4B (show CHMP4A Antibodies), through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

  6. CHMP4B (show CHMP4A Antibodies) interacts directly with CC2D1A (show CC2D1A Antibodies) and CC2D1B (show CC2D1B Antibodies) with nanomolar affinity by forming a 1:1 complex.

  7. CC2D1A (show CC2D1A Antibodies) interaction with CHMP4B (show CHMP4A Antibodies)/4A blocks HIV-1 budding.

  8. hSnf7-1 and hSnf7-2 are preferentially associated with CHMP2A (show CHMP2A Antibodies) and CHMP2B (show CHMP2B Antibodies), respectively, and regulate the turnover of distinct transmembrane cargos such as neurotransmitter receptors in human neurons.

  9. CHMP4b (show CHMP4A Antibodies) and Alix (show PDCD6IP Antibodies) participate in formation of multivesicular bodies by cooperating with SKD1 (show vps4b Antibodies)

  10. ALIX (show PDCD6IP Antibodies) can have a dramatic effect on HIV-1 release by binding at the CHMP4B (show CHMP4A Antibodies) site; the ability to use ALIX (show PDCD6IP Antibodies) may allow HIV-1 to replicate in cells that express only low levels of Tsg101 (show TSG101 Antibodies)

Mouse (Murine) Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. CHMP4B, through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

CHMP4B Antigen Profile

Protein Summary

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

Gene names and symbols associated with CHMP4B

  • charged multivesicular body protein 4B (CHMP4B) antibody
  • charged multivesicular body protein 4B (Chmp4b) antibody
  • charged multivesicular body protein 4Ba (chmp4ba) antibody
  • charged multivesicular body protein 4B L homeolog (chmp4b.L) antibody
  • charged multivesicular body protein 4Bb (chmp4bb) antibody
  • 2010012F05Rik antibody
  • c20orf178 antibody
  • C76846 antibody
  • CHMP4A antibody
  • chmp4b antibody
  • chmp4b.S antibody
  • CHMP4c antibody
  • CTPP3 antibody
  • CTRCT31 antibody
  • dJ553F4.4 antibody
  • RGD1309846 antibody
  • RGD1565889 antibody
  • Shax1 antibody
  • SNF7 antibody
  • Snf7-2 antibody
  • Vps32-2 antibody
  • VPS32B antibody
  • wu:fc96b02 antibody
  • zgc:55566 antibody

Protein level used designations for CHMP4B

SNF7 homolog associated with Alix 1 , Snf7 homologue associated with Alix 1 , charged multivesicular body protein 4b , chromatin modifying protein 4B , chromatin-modifying protein 4b , hSnf7-2 , hVps32-2 , vacuolar protein sorting-associated protein 32-2 , vacuolar protein-sorting-associated protein 32-2 , CHMP4b , Chromatin-modifying protein 4b , charged multivesicular body protein 4B S homeolog , CHMP4c , Chromatin-modifying protein 4c , charged multivesicular body protein 4B , charged multivesicular body protein 4c , chromatin-modifying protein 4c

GENE ID SPECIES
128866 Homo sapiens
75608 Mus musculus
419150 Gallus gallus
393164 Danio rerio
100359642 Rattus norvegicus
495125 Xenopus laevis
100714567 Cavia porcellus
406766 Danio rerio
485842 Canis lupus familiaris
616164 Bos taurus
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