anti-Collagen and Calcium Binding EGF Domains 1 (CCBE1) Antibodies

CCBE1 encodes a protein containing an emilin domain and two collagen stretches. Additionally we are shipping CCBE1 Kits (5) and CCBE1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCBE1 147372 Q6UXH8
CCBE1 320924 Q3MI99
CCBE1 361341  
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Top anti-CCBE1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CCBE1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CCBE1 expression in ACHN (A), HeLa (B), SP2/0 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of CCBE1 using HUVEC whole cell lysates ABIN6272568 at 1/100 staining Human lymph node tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB CCBE1 Antibody (Center)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the CCBE1 antibody detected the CCBE1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in MCF-7 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IF, WB Immunofluorescence staining (green) of human foreskin (cryo-section of unfixed tissue) with anti human ccbe1 (dilution 1/50) Cat.-No AP26020PU-N. A) Note specific staining in epidermis (ep) and in scattered cells in the dermis. B) Negative control of a consecutive section. Nuclei counter-stained with Dapi (blue). Specimen provided by Prof. Dr. J. Wilting, Goettingen. 0.1 mg Log in to see 6 to 8 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 11 to 13 Days
$335.04
Details

More Antibodies against CCBE1 Interaction Partners

Human Collagen and Calcium Binding EGF Domains 1 (CCBE1) interaction partners

  1. Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1.

  2. the present results demonstrated that CCBE1 expression was downregulated in lung cancer, particularly in the presence of LNM.

  3. these data indicated that CCBE1 may be served as a new predictor of prognosis in post-operative gastrointestinal stromal tumor patients and may play an important role in stimulating tumor progression

  4. We identify CCBE1 as a direct target of miR-330-3p, and show that knockdown of CCBE1 results in a greater invasive capacity. Accordingly, in breast cancer patients CCBE1 is frequently downregulated, and its loss is associated with reduced distant relapse-free and overall survival.

  5. characterization of Hennekam Syndrome phenotypes in two Turkish siblings with protein mutation

  6. Collagen domains of CCBE1 are crucial for the activation of VEGFC in vitro and in vivo. The EGF domains of CCBE1 are dispensable for regulation of VEGFC processing in vitro, however, they are necessary for full lymphangiogenic activity of CCBE1 in vivo.

  7. CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation.

  8. Both siblings harbored a homozygous mutation in CCBE1.

  9. The study has shown that CCBE1 mutations are not a major contributor to non-immune hydrops fetalis.

  10. Human CCBE1 strongly enhances vascular endothelial growth factor-C-mediated lymphangiogenesis in a corneal micropocket assay

  11. Loss of CCBE1 expression may promote ovarian carcinogenesis by enhancing migration & cell survival. CCBE1 is a new candidate tumour suppressor in ovarian cancer.

  12. Homozygous cysteine to serine change and SNPS in CCBE1 were identified patients.

  13. Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans

Mouse (Murine) Collagen and Calcium Binding EGF Domains 1 (CCBE1) interaction partners

  1. During mouse embryonic stem cell (ESC) differentiation Ccbe1 is upregulated upon emergence of Isl1- and Nkx2.5- positive cardiac progenitors. Ccbe1 is enriched in Isl1-positive cardiac progenitors isolated from ESCs differentiating in vitro or embryonic hearts developing in vivo. Disruption of Ccbe1 activity by shRNA knockdown or blockade with a neutralizing antibody results in impaired differentiation of ESCs.

  2. Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1.

  3. CCBE1 is essential for coronary vessel formation, independent of their embryonic origin, and is also necessary for peritruncal vessel growth and proper CA stem patterning.

  4. Collagen domains of CCBE1 are crucial for the activation of VEGFC in vitro and in vivo. The EGF domains of CCBE1 are dispensable for regulation of VEGFC processing in vitro, however, they are necessary for full lymphangiogenic activity of CCBE1 in vivo.

  5. CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation.

  6. Ccbe1 has an essential role in lymphangiogenesis [review]

  7. The secreted lymphangiogenic protein CCBE1 is essential for fetal but not postnatal erythropoiesis.

  8. Ccbe1 expression marks the cardiac and lymphatic progenitor lineages during early stages of mouse development

  9. Phenotypic analysis of murine Ccbe1 mutant embryos show a complete lack of definitive lymphatic structures, even though lymphatic endothelial cells are specified within the cardinal vein

Zebrafish Collagen and Calcium Binding EGF Domains 1 (CCBE1) interaction partners

  1. Collagen domains of CCBE1 are crucial for the activation of VEGFC in vitro and in vivo. The EGF domains of CCBE1 are dispensable for regulation of VEGFC processing in vitro, however, they are necessary for full lymphangiogenic activity of CCBE1 in vivo.

  2. In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1, and Vegfc-driven sprouting is enhanced by local Ccbe1 overexpression. Moreover, Vegfc- and Vegfr3-dependent Erk signaling is impaired in the absence of Ccbe1.

CCBE1 Antigen Profile

Protein Summary

This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans.

Gene names and symbols associated with CCBE1

  • collagen and calcium binding EGF domains 1 (CCBE1) antibody
  • collagen and calcium binding EGF domains 1 (Ccbe1) antibody
  • collagen and calcium binding EGF domains 1 (ccbe1) antibody
  • 4933426F18Rik antibody
  • 9430093N24Rik antibody
  • fof antibody
  • mKIAA1983 antibody
  • RGD1307670 antibody

Protein level used designations for CCBE1

collagen and calcium-binding EGF domain-containing protein 1 , full of fluid protein homolog , collagen and calcium binding EGF domains 1 , full of fluid protein , LOW QUALITY PROTEIN: collagen and calcium-binding EGF domain-containing protein 1

GENE ID SPECIES
147372 Homo sapiens
320924 Mus musculus
361341 Rattus norvegicus
455449 Pan troglodytes
534569 Bos taurus
555629 Danio rerio
610092 Canis lupus familiaris
702222 Macaca mulatta
770043 Gallus gallus
100593092 Nomascus leucogenys
100727972 Cavia porcellus
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