DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) ELISA Kits

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3B Antibodies (135) and DNMT3B Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT3B 1789 Q9UBC3
DNMT3B 444985  
DNMT3B 13436 O88509
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Top DNMT3B ELISA Kits at antibodies-online.com

Showing 4 out of 17 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.045 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$757.89
Details
Human 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Rat 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
$638.00
Details
Human
  96 Tests Log in to see 31 to 41 Days
$541.20
Details

More ELISA Kits for DNMT3B Interaction Partners

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation content are rather a function of time, and not a genetic component.

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a and DNMT3b were associated with several beef quality traits.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. results of this analysis indicating a role for DNMT3B7 in tumor progression of many additional cancer types.

  2. DNMT1 expression associated with extracapsular nodal extension. DNMT3A and DNMT3B expression showed a significant association with high histologic grade and DNMT3A expression was also associated with HER-2 status. overexpression of DNMT3B remained as an independent and unfavorable prognostic factor for disease free survival.

  3. The following meta-analysis involved only Chinese population and further confirmed the significant association of -579G>T with gastric cancer but not lung cancer and suggested no significant association between -149C>T and risk of lung or gastric cancer. Collectively, DNMT3B -579G>T polymorphism is associated with gastric cancer risk in Chinese population

  4. Among 9 candidate genes, GNB4 was identified and validated by qRT-PCR as a potential target silenced by DNA methylation via DNA methyltransferase 3B (DNMT3B).

  5. Study suggests a role for DNMT3B in leukemogenesis in inv(16) acute myeloid leukemia, through MN1 methylation regulation.

  6. Data indicate a role for DNA methyltransferase 3B (DNMT3B) suggesting that it might substitute for the absent accessory protein DNMT3L to recruit DNMT3A in somatic cells.

  7. These results provided evidence that the DNMT3B -283T>C polymorphism might significantly contribute to the lung cancer risk in the Asian population, but not the gastric cancer risk in the Chinese population.

  8. There was no significant difference in the distribution of DNMT3B -579 G>T genotypes between the cases and controls.

  9. The epigenetic targets AURKB, AURKC and DNMT3B, and the global DNA methylation profile are regulated during HIV-1 replication in CD4+ T cells, and this regulation can be influenced by the activation state of the cell at the time of infection.

  10. Data suggest that female patients carrying the rs2424932 or rs998382 variants of DNA methyltransferase 3b (DNMT3) were more likely to develop Parkinson's disease (PD) than female controls.

  11. Our study expands the mutation spectrum in ICF syndrome and supports that DNMT3B and ZBTB24 are the most common disease genes

  12. Alternative splice variant of DNMT3B is associated with leukemia.

  13. these results provided a plausible link between the observed reduction of miR-26a and MEG3 in HCCs. Together, the present study added miR-26a/DNMT3B/MEG3 axis to the complex mechanisms of HCC development.

  14. Results show that DNMT1 mRNA levels were significantly higher in alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma tumors compared to normal skeletal muscle. Thse data indicate that altered expression of DNMT3B plays a key role in embryonal rhabdomyosarcoma development since its silencing is able to reverse cell cancer phenotype by rescuing myogenic program.

  15. The present study shows that DNMT3B rs2424913 promotor polymorphism represents a genetic risk factor that may play an important role in understanding the pathogenesis of chronic immune thrombocytopenia.

  16. LMP1-mediated NF-kappaB can up-regulate DNMT3b transcription, thereby leading to relatively higher methylation intensity at PTEN CpG islands, and ultimately silencing major tumor suppressor PTEN

  17. DNMT1, DNMT3A, and DNMT3B were overexpressed in 36.9, 26, and 23 % of the OSCC patients, respectively. DNMT1 overexpression was significantly associated with the overall survival, p = 0.029, and relapse-free survival of OSCC patients, p = 0.003. Patients with DNMT1 overexpression, as an independent prognostic factor, had a 2.385 times higher risk to relapse than those with lower expression. The DNMT1 A201G gene polymorphi

  18. report the first crystal structure of the DNMT3B PWWP domain-H3K36me3 complex.

  19. Results continue to establish ANG as an oncoprotein and further reveal that ANG contributes to oncogenesis by the activation of MMP2 through modulation of DNMT3b functions.

  20. found association between DNMT3B rs2424913 in T allele carriers with Parkinson's disease

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. The epiblast expressed epithelial markers, MUC1 and E-CADHERIN, and the pluripotency markers, DNMT3B and CRIPTO.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Deletion of the de novo DNA methyltransferases Dnmt3a and Dnmt3b in mouse B cells results in normal B cell development and maturation, but increased cell activation and expansion of the germinal center B cell and plasma cell populations upon immunization.

  2. this study shows that Rbm10 regulates inflammation development via alternative splicing of Dnmt3b

  3. We further demonstrated that ectopic expression of Dnmt3b in AG-haESCs could effectively improve DNA methylation level, and the high incidence of self-diploidization could be markedly rescued

  4. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1, DNMT3A, and DNMT3B proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  5. Altogether, the authors demonstrate that Dnmt3a and Dnmt3b protect the epidermis from tumorigenesis and that squamous carcinomas are sensitive to inhibition of PPAR-gamma.

  6. a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B and non-CpG methylation.

  7. Together, this study described the regulation of Chk2 expression through promoter methylation by Dnmt3b and also presented a novel role of Chk2 during neuronal differentiation, which is independent of its previously known function in DNA damage response.

  8. Mutation of all three Dnmts resulted in global genomic hypomethylation and dramatic reorganization of the photoreceptor and synaptic layers within retina. Transcriptome and proteomic analyses demonstrated enrichment of dysregulated phototransduction and synaptic genes.

  9. in mouse embryonic stem cells, Dnmt3b-dependent intragenic DNA methylation protects the gene body from spurious RNA polymerase II entry and cryptic transcription initiation

  10. three DNA methyltransferases, Dnmt1, Dnmt3a, and Dnmt3b, have been identified. Dnmt3a and Dnmt3b are responsible for establishing DNA methylation patterns produced through their de novo-type DNA methylation activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l), which is a member of the Dnmt3 family but does not possess DNA methylation

  11. While lens epithelial cell survival requires DNMT1, morphologically normal lenses develop in the absence of both DNMT3A and DNMT3B.

  12. Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.

  13. a miR-125b-DNMT3b-p53 signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.

  14. miR-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b and SET1A expression in hepatic stellate cells.

  15. Loss of DNMT3B results in hypomethylation of the miR-196b promoter and increased miR-196b expression, which directly targets the mTORC2 component Rictor.

  16. The findings define PRMT7 as a regulator of the DNMT3b/p21 axis required to maintain muscle stem cell regenerative capacity.

  17. These results demonstrate that Dnmt1 and Dnmt3b cooperate to maintain DNA methylation and genomic integrity in the intestinal epithelium.

  18. Downregulation of DNMT3B, one of the targets identified using this method, radiosensitizes cancer cells by disturbing multiple DNA damage responses.

  19. High levels of Dnmt3b expression prolong leukemia latency.

  20. The expression of DNMT1 and DNMT3b was decreased at 1 mT, and 50 Hz ELF-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF-EMF exposure

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. dnmt7 specifically methylates no tail gene in the genome

DNMT3B Antigen Profile

Antigen Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Gene names and symbols associated with DNMT3B

  • DNA methyltransferase 3 beta (DNMT3B) antibody
  • DNA methyltransferase 3 beta (Dnmt3b) antibody
  • DNA methyltransferase 3 beta (dnmt3b) antibody
  • DNA methyltransferase 3B (Dnmt3b) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba) antibody
  • cb91 antibody
  • DNMT3B antibody
  • dnmt3bl antibody
  • dnmt7 antibody
  • ICF antibody
  • ICF1 antibody
  • LOC100218113 antibody
  • M.HsaIIIB antibody
  • MmuIIIB antibody
  • sb:cb91 antibody
  • wu:fb16h07 antibody

Protein level used designations for DNMT3B

DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta , DNA MTase HsaIIIB , DNA methyltransferase 3B , DNA (cytosine-5)-methyltransferase 3B-like , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B

GENE ID SPECIES
458174 Pan troglodytes
419287 Gallus gallus
711553 Macaca mulatta
100053900 Equus caballus
353354 Bos taurus
100218113 Taeniopygia guttata
1789 Homo sapiens
444985 Rattus norvegicus
100302109 Sus scrofa
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
13436 Mus musculus
321084 Danio rerio
100731772 Cavia porcellus
100685634 Canis lupus familiaris
100349823 Oryctolagus cuniculus
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