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DPH3 encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. Additionally we are shipping DPH3 Antibodies (6) and many more products for this protein.
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The results from this study show occurrence of frequent somatic non-coding mutations adjacent to a pre-existing binding site for Ets transcription factors within the directional promoter of DPH3 and OXNAD1 genes in three major skin cancers.
DelGIP1is a binding partner of deafness locus putative guanine nucleotide exchange factor (show RASGRF1 Proteins); downregulation of DelGIP1 induced increased extracellular secretion of proteoglycans indicating a possible role for DelGIP1 in the secretion process
Solution structure of human DESR1, a CSL zinc-binding protein.
we found that Dph3 promotes melanoma migration and invasion through the AKT (show AKT1 Proteins) signaling pathway.
This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.
CSL-type zinc finger-containing protein 2
, DPH3 homolog
, DPH3 homolog (KTI11, S. cerevisiae)
, DPH3, KTI11 homolog
, DPH3A, KTI11 homolog A
, Del-GEF interacting protein
, deafness locus putative guanine nucleotide exchange factor interacting protein 1
, delGEF-interacting protein 1
, diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1
, zinc finger, CSL domain containing 2
, zinc finger, CSL-type containing 2