HLA Class II DO alpha Proteins (HLA-DOA)

HLA-DOA belongs to the HLA class II alpha chain paralogues. Additionally we are shipping HLA-DOA Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLA-DOA 3111 P06340
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Top HLA-DOA Proteins at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days

HLA-DOA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for HLA Class II DO alpha (HLA-DOA) Interaction Partners

Human HLA Class II DO alpha (HLA-DOA) interaction partners

  1. Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

  2. significant association was found between white wine liking and rs9276975:C>T polymorphism in the HLA-DOA gene.

  3. TAP2 (show TAP2 Proteins), HLA-DOA, HLA-DOB (show HLA-DOB Proteins), and tapasin (show TAPBP Proteins) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  4. HLA-DO regulates surface presentation of human leukocyte antigen class II (show HLA-DRB5 Proteins)-restricted antigens on B cell malignancies.

  5. HLA-DOA, HLA-DRA, and HLA-DQA1 associated with spontaneous autoimmunity

  6. HLA-DOA mutations were analyzed for association with autoimmune diseases and B-cell leukemias.

  7. In transgenic mice expressing human HLA-DOA & HLA-DOB from a DC-specific promoter, as DO increased, A(b)-CLIP increased & class II-peptides decreased. DO impaired H-2M function, causing Ag-specific downmodulation of class II Ag processing/presentation.

  8. four novel HLA-DOA alleles, DOA*010106, DOA*0102, DOA*0103, and DOA*0104N, were identified by sequence-based typing

  9. minor allele of the SNP rs9296068 is significantly associated with liver transplantation rejection and with enhanced B-lymphocyte (show AKAP17A Proteins) participation in rejection, likely because of a dysfunctional HLA-DOA gene product.

  10. HLA-DOA polymorphisms are associated with Diabetes Mellitus, Type 1.

HLA-DOA Protein Profile

Protein Summary

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Gene names and symbols associated with HLA-DOA

  • major histocompatibility complex, class II, DO alpha (HLA-DOA)
  • HLA-DNA protein
  • HLA-DZA protein
  • HLADZ protein

Protein level used designations for HLA-DOA

HLA class II histocompatibility antigen, DO alpha chain , HLA-D0-alpha , MHC DN-alpha , MHC DZ alpha , MHC class II antigen DOA , lymphocyte antigen , major histocompatibility complex, class II, DN alpha

3111 Homo sapiens
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