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KIR2DS3 Proteins

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 3 (KIR2DS3))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
KIR2DS3 Protein (Myc-DYKDDDDK Tag) KIR2DS3 Protein (Myc-DYKDDDDK Tag) KIR2DS3 Protein (Myc-DYKDDDDK Tag) (ABIN2724259)

KIR2DS3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

KIR2DS3 Proteins by Origin

Find KIR2DS3 Proteins for a variety of species such as anti-Human KIR2DS3. The species listed below are among those available. Click on a link to go to the corresponding products.

KIR2DS3 Proteins by Source

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KIR2DS3 Proteins by Protein Type

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KIR2DS3 Proteins by Application

Find KIR2DS3 Proteins validated for a specific application such as AbP, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular KIR2DS3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724259
Quantity 20 μg
Datasheet Datasheet

Aliases for KIR2DS3 Proteins

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3 (KIR2DS3) Proteins
NKAT7 Proteins
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