anti-Laminin, gamma 3 (LAMC3) Antibodies

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. Additionally we are shipping Laminin, gamma 3 Proteins (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAMC3 23928 Q9R0B6
LAMC3 10319 Q9Y6N6
LAMC3    
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Top anti-Laminin, gamma 3 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LAMC3 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell LAMC3 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LAMC3 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of LOVO cells, using LAMC3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: LAMC3 Antibody [NBP2-33895] - liver cancer Immunohistochemistry: LAMC3 Antibody [NBP2-33895] - Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocyte. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see Available
$181.73
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p) 100 μL Log in to see 11 to 14 Days
$493.17
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Human Spleen Tissue 100 μg Log in to see 13 to 16 Days
$360.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Mouse Liver Tissue 100 μg Log in to see 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of LAMC3 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide. ABIN6273513 at 1/100 staining Human lung cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IF, IHC (p), WB 200 μL Log in to see 12 to 14 Days
$438.90
Details

More Antibodies against Laminin, gamma 3 Interaction Partners

Mouse (Murine) Laminin, gamma 3 (LAMC3) interaction partners

  1. Deletion of Lamb2 and Lamc3 genes affects astrocyte migration and spatial patterning in the retina.

  2. gamma3-containing laminins are expressed in a wide variety of basement membranes. gamma3 is expressed in CNS but not peripheral vascular basement membranes.

  3. a strong impact of laminin beta2 and gamma3 subunits on the expression and function of both aquaporin-4 and Kir4.1, two important membrane proteins in Muller cells.

  4. In human but not mouse fetal brain, LAMC3 is enriched in postmitotic cortical plate neurons, localizing primarily to the somatodendritic compartment.

  5. Laminin gamma3 chain, located in murine basement membranes, binds to nidogen

  6. netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms

Human Laminin, gamma 3 (LAMC3) interaction partners

  1. LAMC3 gene variation is associated with oral cavity and pharyngeal cancer.

  2. We found statistically significant association with AAO for three genes (WRN, NTN4 and LAMC3) with common associated variants.

  3. These data suggest that beta2 and gamma3-containing laminins play an important dose-dependent role in development of the cortical pial basement membrane

  4. Recessive LAMC3 mutations cause malformations of occipital cortical development.

  5. Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains

Laminin, gamma 3 (LAMC3) Antigen Profile

Protein Summary

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 3. The gamma 3 chain is most similar to the gamma 1 chain, and contains all the 6 domains expected of the gamma chain. It is a component of laminin 12. The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. In skin, it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration. Gamma 3 is also a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells.

Gene names and symbols associated with LAMC3

  • laminin gamma 3 (Lamc3) antibody
  • laminin subunit gamma 3 (LAMC3) antibody
  • AI562206 antibody
  • AW240805 antibody
  • OCCM antibody

Protein level used designations for LAMC3

laminin subunit gamma-3 , laminin-12 subunit gamma , laminin-14 subunit gamma , laminin-15 subunit gamma

GENE ID SPECIES
23928 Mus musculus
10319 Homo sapiens
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