anti-Lysyl Oxidase (LOX) Antibodies

The protein encoded by LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. Additionally we are shipping LOX Kits (54) and LOX Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LOX 4015 P28300
LOX 16948 P28301
LOX 24914 P16636
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Top anti-LOX Antibodies at antibodies-online.com

Showing 10 out of 190 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Simple Western: LOX Antibody [ABIN4331341] - Simple Western lane view shows a specific band detected for LOX in HeLa lysate. This experiment was performed under reducing conditions using the Wes or Sally Sue separation system 12-230kDa (or 66-440kDa). Simple Western: LOX Antibody [ABIN4331341] - Simple Western lane view shows a specific band for LOX in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230kDa separation system. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Staining of LOPP in mouse intestine using ABIN258371. Western Blot: LOX propeptide Antibody [ABIN2583718] - Detection of LOPP in MC3T3-E1 cell lysate. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IP, SimWes, WB Flow Cytometry: LOX propeptide Antibody [NBP1-30327] - Staining of NTERA-2 cells using NP1-30327 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary antibody. Immunocytochemistry/Immunofluorescence: LOX propeptide Antibody [NBP1-30327] - Staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Cow Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Immunohistochemistry: LOX Antibody [ABIN250966] - Human placental villi, 40X. Staining of placental trophoblasts using ABIN250966 at 10 ug/ml. Detection of LOX in mouse kidney lysate using ABIN250966 (1:1,000). ECL detection was 15 sec. 0.05 mL Log in to see 7 to 9 Days
$444.19
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, WB Staining of LOX in mouse spleen using ABIN258622. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: LOX Antibody [ABIN4331347] - Analysis of LOX in human kidney Immunocytochemistry/Immunofluorescence: LOX Antibody [ABIN4331347] - LOX antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 7 to 9 Days
$444.19
Details

Top referenced anti-LOX Antibodies

  1. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN4331341 : Ovchinnikova, Robertson, Wågsäter, Folco, Hyry, Myllyharju, Eriksson, Libby, Hansson: T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. in The American journal of pathology 2009 (PubMed)
    Show all 17 Pubmed References

  2. Cow (Bovine) Polyclonal LOX Primary Antibody for ICC, IF - ABIN4331351 : Atsawasuwan, Mochida, Katafuchi, Kaku, Fong, Csiszar, Yamauchi: Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity. in The Journal of biological chemistry 2008 (PubMed)
    Show all 14 Pubmed References

  3. Cow (Bovine) Polyclonal LOX Primary Antibody for ICC, IF - ABIN250966 : Wilhelmus, Bol, van Duinen, Drukarch: Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type. in Experimental gerontology 2013 (PubMed)
    Show all 10 Pubmed References

  4. Human Polyclonal LOX Primary Antibody for ICC, IHC (fro) - ABIN258622 : Jeay, Pianetti, Kagan, Sonenshein: Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. in Molecular and cellular biology 2003 (PubMed)
    Show all 9 Pubmed References

  5. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN258371 : Palamakumbura, Jeay, Guo, Pischon, Sommer, Sonenshein, Trackman: The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal LOX Primary Antibody for FACS, ICC - ABIN447477 : Sato, Trackman, Mäki, Myllyharju, Kirsch, Sonenshein: The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. in Molecular and cellular biology 2011 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal LOX Primary Antibody for WB - ABIN1882262 : Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal LOX Primary Antibody for WB - ABIN1882261 : Santhanam, Baker, Hegamyer, Kirschmann, Colburn: Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. in Oncogene 2010 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN440592 : Di Stefano, Torsello, Bianchi, Cifola, Mangano, Bovo, Cassina, De Marco, Corti, Meregalli, Bombelli, Viganò, Battaglia, Strada, Perego: Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures. in The American journal of pathology 2016 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN4331347 : Contente, Yeh, Friedman: Tumor suppressive effect of lysyl oxidase proenzyme. in Biochimica et biophysica acta 2009 (PubMed)

More Antibodies against LOX Interaction Partners

Zebrafish Lysyl Oxidase (LOX) interaction partners

  1. Partial knockdown of lysyl oxidase genes sensitizes the developing embryo to dithiocarbamate exposure.

  2. Data reveal a role for lysyl oxidase in early morphogenesis, especially in muscle development and neurogenesis, and resume some aspects of physiopathology of copper metabolism.

Human Lysyl Oxidase (LOX) interaction partners

  1. this study has revealed that IL-1beta (show IL1B Antibodies) may contribute to the rupture of fetal membranes by attenuating collagen crosslinking through downregulation of LOX expression in amnion fibroblasts

  2. This study focused on the relationship between lysyl oxidase (LOX), LOX-like protein 1 (LOXL1 (show LOXL1 Antibodies)), and LOXL2 (show LOXL2 Antibodies) and pulmonary emphysema pathogenesis.

  3. The aim was to examine if the serum concentrations of elastin (show ELN Antibodies)-related proteins correlate to signs of cardiovascular diseases in patients with Diabetes mellitus type 2.

  4. LOX role in cancer stromal cells activation and promotion of gastric cancer progression

  5. an association of LOX gene polymorphism (G473A) on diabetes and DFU patients

  6. LOX expression was mildly but significantly upregulated in CD34 (show CD34 Antibodies)+-derived primary myelofibrosis megakaryocytes and platelets compared with controls. These megakaryocytes showed a greater tendency to adhere and spread to monomeric collagen, and this was inhibited by the LOX-specific inhibitor BAPN (show ANPEP Antibodies).

  7. Data suggest that a missense mutation in lysyl oxidase (LOX) is associated with aortic disease.

  8. Our findings suggest that LOX has a role in cancer cell mitosis

  9. Our findings provide new evidence that LOX regulates SNAI2 expression and that SNAI2-mediated TIMP4 (show TIMP4 Antibodies) secretion plays a role in cancer progression.

  10. UXT (show UXT Antibodies) Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha (show ESR1 Antibodies) Activity in Breast Cancer Cells.

Pig (Porcine) Lysyl Oxidase (LOX) interaction partners

  1. Statins normalize vascular lysyl oxidase (LOX) down-regulation induced by proatherogenic risk factors.

Cow (Bovine) Lysyl Oxidase (LOX) interaction partners

  1. These results indicate that proLOX could be processed by two different mechanisms producing two forms of active LOX.

  2. Lysyl oxidase enhances elastin (show ELN Antibodies) synthesis and matrix formation by vascular smooth muscle cells

  3. Lysyl oxidase has a role in oxidizing basic fibroblast growth factor (show FGF2 Antibodies) and inactivating its mitogenic potential

  4. In cases of vascular calcification, the decreased expression of LOX may be partially responsible for decreased vascular elasticity and also for the decreased formation of new elastic fibers.

  5. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.

Mouse (Murine) Lysyl Oxidase (LOX) interaction partners

  1. LOX over-expression in vascular smooth muscle cells was associated with a change in the structure of collagen and elastin (show ELN Antibodies) fibres; LOX could constitute a novel source of oxidative stress that might participate in elastin (show ELN Antibodies) changes and contribute to vascular remodelling

  2. LOX up-regulation is associated with enhanced oxidative stress that promotes p38MAPK (show MAPK14 Antibodies) activation, elastin (show ELN Antibodies) structural alterations, and vascular stiffness.

  3. These results suggest that LOX has the ability to induce RANKL (show TNFSF11 Antibodies) expression on stromal cells; however, it fails to substitute for RANKL (show TNFSF11 Antibodies) in osteoclastogenesis.

  4. UXT (show UXT Antibodies) Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha (show ESR1 Antibodies) Activity in Breast Cancer Cells.

  5. Data show that LOX-PP enhances adipogenesis at least partially through inhibition of FGF-2 (show FGF2 Antibodies) receptor signaling.

  6. LOX targeting reduces peritoneal fibrosis.

  7. Absence of lysyl oxidase (Lox) causes thoracic aortic aneurysms. The aortic mechanical behavior of Lox(-/-) mice is consistent with reduced elastin (show ELN Antibodies) and collagen cross-linking but demonstrates vascular location-specific differences. Lox(-/-) aortas show upregulation of matrix remodeling genes and location-specific differential expression of other matrix and smooth muscle cell gene sets.

  8. Findings from this study indicate that preventing LOX overexpression may be protective against high glucose-induced apoptosis in retinal vascular cells associated with diabetic retinopathy.

  9. LOX family members contribute significantly to the detrimental effects of cardiac remodelling, highlighting LOX inhibition as a potential therapeutic strategy for post-infarction recovery

  10. Findings suggest that the lysyl oxidase (LOX)-mediated organization of collagen fibers in the extracellular matrix is an important regulator of osteoblastogenesis.

LOX Antigen Profile

Protein Summary

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Lysyl Oxidase (LOX) Antibodies

  • lysyl oxidase (LOX) antibody
  • lysyl oxidase (lox) antibody
  • lysyl oxidase a (loxa) antibody
  • lysyl oxidase L homeolog (lox.L) antibody
  • lysyl oxidase (Lox) antibody
  • AI893619 antibody
  • H-rev142 antibody
  • lox antibody
  • MGC146507 antibody
  • Rrg1 antibody
  • TSC-160 antibody
  • Xlox antibody
  • zgc:77447 antibody

Protein level used designations for anti-Lysyl Oxidase (LOX) Antibodies

lysyl oxidase , protein-lysine 6-oxidase-like , protein-lysine 6-oxidase , ras excision protein , ras recision gene (rrg) , Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)

GENE ID SPECIES
471614 Pan troglodytes
699997 Macaca mulatta
780067 Xenopus (Silurana) tropicalis
100189621 Oncorhynchus mykiss
100457685 Pongo abelii
404621 Danio rerio
734204 Xenopus laevis
4015 Homo sapiens
100525278 Sus scrofa
280841 Bos taurus
16948 Mus musculus
24914 Rattus norvegicus
396474 Gallus gallus
481478 Canis lupus familiaris
100720740 Cavia porcellus
100357045 Oryctolagus cuniculus
101112220 Ovis aries
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