anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Antibodies

Histone methyltransferase that plays an essential role in early development and hematopoiesis.

Type
  • 10
    Primary antibodies
Antigen
  • 10
Reactivity
  • 10
  • 1
Application
  • 8
  • 2
  • 1
  • 1
Detection Method
  • 3
Host
  • 10
Clonality
  • 10
Binding Specificity
  • 7
  • 7
Conjugate
  • 4
  • 1
  • 1
  • 1
  • 1
Isotype
  • 9
Format
  • 10
10 Products
ReactivityHuman
Application WB
Order details Cat. No. ABIN2146664
$507.57
100 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine)
Application WB
Order details Cat. No. ABIN223468
$280.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ChIP-seq, ChIP, ELISA
Order details Cat. No. ABIN6952424
$495.00
100 μL
Plus shipping costs $45.00
Delivery in 7 to 9 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321592
$594.00
200 μL
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321574
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321577
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321580
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321583
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321586
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN2321589
$743.29
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
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Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antigen Profile

Protein Summary

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Gene names and symbols associated with MLL1

  • lysine methyltransferase 2A (Kmt2a) antibody
  • lysine (K)-specific methyltransferase 2A (Kmt2a) antibody
  • 6430520K01 antibody
  • ALL-1 antibody
  • All1 antibody
  • Cxxc7 antibody
  • HRX antibody
  • HTRX1 antibody
  • mKIAA4050 antibody
  • Mll antibody
  • Mll1 antibody

Protein level used designations for MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPECIES
315606 Rattus norvegicus
214162 Mus musculus