anti-Myosin Light Chain Kinase (MYLK) Antibodies

MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. Additionally we are shipping Myosin Light Chain Kinase Kits (36) and Myosin Light Chain Kinase Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYLK 4638 Q15746
MYLK 288057  
MYLK 107589  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Myosin Light Chain Kinase Antibodies at antibodies-online.com

Showing 10 out of 124 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB Western blot analysis of MLCK1 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: Myosin light chain kinase Antibody (SU40-06)  - Analysis of SH-SY-5Y cells with MYLK antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. Immunocytochemistry/Immunofluorescence: Myosin light chain kinase Antibody (SU40-06)  - Staining MYLK in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 100 μL Log in to see 34 Days
$373.75
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MYLK3 Antibody (N-term) (ABIN392494) in A375 cell line lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-MYLK3 Antibody (N-term) (ABIN392494) in mouse heart tissue lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Western blot analysis in K562 cell line lysates (35ug/lane) using MLCK Antibody . This demonstrates this antibody detected the MLCK protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Rat Prostate Gland Tissue; Lane3: Rat Bladder Tissue. 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Mouse Stomach Tissue. 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extracts of Mouse uterus, using MYLK antibody. Immunohistochemistry of paraffin-embedded human gastric using MYLK antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Myosin light chain kinase Antibody [NBP1-87744] - Staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells. Western Blot: Myosin light chain kinase Antibody [NBP1-87744] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10 Lane 2: Human cell line HEL 0.1 mL Log in to see 10 to 13 Days
$491.63
Details

Top referenced anti-Myosin Light Chain Kinase Antibodies

  1. Human Polyclonal MYLK Primary Antibody for IHC (p), WB - ABIN392495 : Rossi, Todd, Daniels, Bazan, Belayev: Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice. in Journal of neurotrauma 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MYLK Primary Antibody for IHC (p), WB - ABIN392494 : Rossi, Ralay Ranaivo, Patel, Chrzaszcz, Venkatesan, Wainwright: Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase. in Journal of neuroscience research 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Myosin Light Chain Kinase Interaction Partners

Human Myosin Light Chain Kinase (MYLK) interaction partners

  1. the MAPKspecific inhibitor SB203580 attenuated the inhibitory effects of 4HPR on the migration of HepG2 cells. Moreover, we also observed that 4HPR inhibited the activation and expression of myosin light chain kinase (MLCK) in HepG2 cells.

  2. Recombinant human MLCK was concentration- and time-dependently degraded by recombinant human MMP9 (show MMP9 Antibodies) in vitro, and this process was prevented by the MMP9 (show MMP9 Antibodies) inhibitor.

  3. High expression of MLCK is correlated with metastatic triple negative breast cancer.

  4. Interaction between kinase domain and regulatory light chain (RLC) substrate is identified in the absence of calmodulin, indicating restored substrate-binding capability due to mechanically induced removal of the auto-inhibitory regulatory region.

  5. loss of MLCK contributes to the migratory properties of epithelial cells resulting from changes in cell-cell and cell-matrix adhesions, and increased epidermal growth factor receptor (show EGFR Antibodies) signaling.

  6. Sixty-seven experienced runners competed in a marathon race. The MLCK genotype (C37885A) of these marathoners was determined. CA heterozygotes for MLCK C37885A might present higher exercise-induced muscle damage after a marathon competition than CC counterparts.

  7. these Acute respiratory distress syndrome (ARDS)-associated MYLK cytosine-guanine dinucleotides with effect modification by ethnicity and local modified cytosine quantitative trait loci suggest that MYLK epigenetic variation and local genetic background may contribute to health disparities observed in ARDS.

  8. mechanical stress and MYLK single nucleotide polymorphism regulate MYLK alternative splicing.

  9. Rebeccamycin attenuates TNF-alpha (show TNF Antibodies)-induced disruption of intestinal epithelial barrier integrity by inducing claudin-5 (show CLDN5 Antibodies) expression and suppressing MLCK production via Chk1 (show CHEK1 Antibodies) activation.

  10. Data show that alterations in myosin light chain kinase activity, claudin-15 (show CLDN15 Antibodies) and claudin-2 (show CLDN2 Antibodies) expression are associated with gluten-induced symptomatology and intestinal permeability changes in diarrhea-predominant irritable bowel syndrome (IBS-D).

Cow (Bovine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. Histamine induces myosin light chain (MLC)phosphorylation via MYLK, suggesting regulatory role for MLC in controlling corneal epithelial permeability.

Rabbit Myosin Light Chain Kinase (MYLK) interaction partners

  1. evaluated the spatial arrangement of the catalytic/regulatory domain, three immunoglobulin-related motifs, one fibronectin-related motif, a repetitive, proline-rich segment, and, at the N-terminus, a unique F-actin-binding domain.

Mouse (Murine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. telokin may play a role in attenuating constitutive myosin light chain phosphorylation

  2. MLCK is linked to timely blastocyst formation, though it is dispensable for oocyte meiotic maturation

  3. NF-kappaB (show NFKB1 Antibodies) novel partner within endothelial cells

  4. MLCK regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism.

  5. nmMlck modulates IL-1beta (show IL1B Antibodies)-mediated downregulation of Cldn5 (show CLDN5 Antibodies) in brain microvascular endothelial cells.

  6. a prominent effect of the multifunctional microRNA-155 in endothelial cells is modulation of phenotype through alterations in RhoA, myosin light chain kinase expression, and actin cytoskeleton organization

  7. CArG element in intron 15 of the mylk1 gene is necessary for maximal expression of the 130-kDa smMLCK and that the 130-kDa smMLCK isoform is specifically required to regulate smooth muscle contractility

  8. In immune-mediated inflammatory bowel disease, tight junction dysregulation and barrier loss is induced by MLCK, but at advanced stages, barrier loss is MLCK-independent.

  9. Claudin-2 (show CLDN2 Antibodies) assumes an important role in colorectal inflammation, and furthermore implicates the involvement of MLCK in colon inflammation.

  10. involved in IL-1beta (show IL1B Antibodies)-induced increase in intestinal permeability

Zebrafish Myosin Light Chain Kinase (MYLK) interaction partners

  1. Conclude that Mlck1a is the subtype of MLCK that contributes to platelet shape change and thrombus formation.

Myosin Light Chain Kinase (MYLK) Antigen Profile

Protein Summary

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Gene names and symbols associated with MYLK

  • myosin light chain kinase (MYLK) antibody
  • myosin light chain kinase (Mylk) antibody
  • myosin, light polypeptide kinase (Mylk) antibody
  • myosin, light chain kinase a (mylka) antibody
  • 9530072E15Rik antibody
  • A930019C19Rik antibody
  • AAT7 antibody
  • AW489456 antibody
  • fj60a06 antibody
  • KRP antibody
  • mlck antibody
  • MLCK1 antibody
  • mlck1a antibody
  • MLCK108 antibody
  • MLCK210 antibody
  • MSTP083 antibody
  • mylk antibody
  • MYLK1 antibody
  • SMMLCK antibody
  • wu:fj60a06 antibody
  • zmlck1 antibody

Protein level used designations for MYLK

kinase-related protein , myosin light chain kinase, smooth muscle , myosin, light polypeptide kinase , smooth muscle myosin light chain kinase , telokin , kinase related protein, telokin , myosin, light chain kinase , MLCK , myosin light chain kinase , myosin light chain kinase, smooth muscle-like , smooth muscle myosin light chain kinase (61-kDa active fragment) , myosin light chain kinase 1 , smooth muscle MLCK

GENE ID SPECIES
4638 Homo sapiens
288057 Rattus norvegicus
338037 Bos taurus
460640 Pan troglodytes
488012 Canis lupus familiaris
715422 Macaca mulatta
100009143 Oryctolagus cuniculus
100481263 Ailuropoda melanoleuca
107589 Mus musculus
396445 Gallus gallus
396848 Sus scrofa
443334 Ovis aries
100714177 Cavia porcellus
569510 Danio rerio
Selected quality suppliers for anti-Myosin Light Chain Kinase (MYLK) Antibodies
Did you look for something else?