anti-Nuclear Factor kappa B (NFkB) Antibodies

NFkB encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. Additionally we are shipping Nuclear Factor kappa B Kits (46) and Nuclear Factor kappa B Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFkB 4790 P19838
NFkB 81736  
NFkB 18033 P25799
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Top anti-Nuclear Factor kappa B Antibodies at

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg 13 to 16 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Formalin-fixed and paraffin embedded mouse kidney labeled with Rabbit Anti-NFKB Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human Raji Cells. 100 μg 15 to 18 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Spleen Tissue; Lane2: Mouse Stomach Tissue; Lane3: Human Raji Cells. 100 μg 15 to 18 Days
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Stomach tissue 100 μg 15 to 18 Days
Chicken Rabbit Un-conjugated ICC, IHC, WB 100 μg 13 to 16 Days
Human Rabbit Un-conjugated WB Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the NFKB antibody detected the NFKB protein (arrow). 400 μL 2 to 3 Days
Human Rabbit Un-conjugated WB Western Blot at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: Raji whole cell lysate Lysates/proteins at 20 ug per lane. 400 μL 2 to 3 Days
Human Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of Human Raji Cells. Western blot analysis of recombinant Human NFkB. 100 μg 11 to 18 Days
Human Rabbit Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days

Top referenced anti-Nuclear Factor kappa B Antibodies

  1. Rat (Rattus) Polyclonal NFkB Primary Antibody for ICC, IHC - ABIN1859998 : Volentine, Ogden, Kortje, Tuma, Sorrell: Role of acetaldehyde in the ethanol-induced impairment of hepatic glycoprotein secretion in the rat in vivo. in Hepatology (Baltimore, Md.) 1987 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Nuclear Factor kappa B Interaction Partners

Human Nuclear Factor kappa B (NFkB) interaction partners

  1. RNF25 plays an essential role in gefitinib resistance of Non-small cell lung cancer by mediating cross-talk between NF-kappaB and ERK pathways.

  2. Molecular docking analysis showed that Wi-A did not disrupt; however, decreased the stability of the NFkappaB-DNA complex. It was supported by downregulation of DNA-binding and transcriptional activities of NFkappaB.

  3. Investigated the role of neddylation in collagen-induced arthritis (CIA); found TNF receptor-associated factor 6 (TRAF6) neddylation at Lys124 was essential for IL-17A-induced NF-kappaB activation in inflammatory arthritis.

  4. ERK/NF- kappa B signaling pathway has a role in the inhibition of tumor growth by amentoflavone in glioblastoma.

  5. preliminary findings suggest that the haplotype of rs28362491 and rs72696119 in NFKB1 could act as a novel genetic marker to predict oral cancer risk in the southeast of China

  6. These findings showed that the role of NF-kappaB1 in humans could be critical for the development of acquired and innate immunity and further highlights the role of human T cells in anti-mycobacterial immunity.

  7. Co-expression of p65 and phosphorylated p105 but not of either p65 or phosphorylated p105 alone was associated with a poor prognosis in surgically resectable non-small cell lung cancer patients.

  8. PRDX1 negatively regulates TLR4 signaling for NFKB activation and autophagy functions such as bactericidal activity, cancer cell migration, and cancer cell invasion by inhibiting TRAF6 ubiquitin-ligase activity.

  9. INHA inhibits BMP9-induced osteogenic differentiation through blocking BMP/Smad signal and activating NF-kappaB signal in mesenchymal stem cells.

  10. In conclusion, the authors suggest that NF-kappaB is capable of enhancing the expression of PCT by either directly activating the transcription of the PCT gene or indirectly modulating the expression of its regulatory component, miR-513b.

  11. The role of the lncRNA FLJ46906 in the aging process via aging associated genes regulated by NF-kappaB and AP-1.

  12. The expression of NF-kappaB is increased in intervertebral disc tissue in patients with disc herniation.

  13. These findings identify a previously unrecognized role of SKP2 in NF-kappaB activation by which SKP2 acts as a secondary receptor to assist IKKbeta delivery to autophagosomes for degradation in a p62-dependent manner.

  14. We show that heterozygous loss-of-function variants in NFKB1 are the most common known monogenic cause of CVID, which results in a temporally progressive defect in the formation of immunoglobulin-producing B cells.

  15. Data suggest a linkage between notch receptor 1 (NOTCH1), IKK-alpha protein (IKKalpha), and NF-kappa B (NF-kappaB) pathway activation in maintaining the CD133(+) stem cutaneous squamous cell carcinoma (cSCC) phenotypes.

  16. TRIM31 upregulated the levels of nuclear p65 by promoting K63-linked polyubiquitination of tumor necrosis factor receptor-associated factor 2 (TRAF2) and sustained the activation of nuclear transcription factor kappa B (NF-kappaB) in pancreatic cancer cells.

  17. NF-kappaB and Syk signaling pathways are instrumental for cancer progression. (Review)

  18. inflammatory markers IL8 and NFKB are reduced in human cells in a process mediated by branched-chain fatty acid vernix-monoacylglycerides

  19. High NF-kappa-B expression is associated with glioblastoma growth.

  20. NFKB1single nucleotide polymorphism rs28362491 was associated with an increased risk of susceptibility to hepatitis C in the Chinese Han population.

Pig (Porcine) Nuclear Factor kappa B (NFkB) interaction partners

  1. endotracheal tube presence was characterized by neutrophil activation, necrosis, and release of proinflammatory cytokines mediated by TLR9/NF-kappaB induction.

  2. Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 and NF-kappaB.

  3. Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.

  4. Porcine parvovirus virus infection significantly induced IL-6 expression and this induction depended on NF-kappaB activation and TLR9 signaling pathways in PK-15 cell.

  5. This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB activity and nsp1 was a potent NF-kappaB antagonist for suppression of both interferon and early production of pro-inflammatory cytokines.

  6. inhibition of NF-kappaB increases autophagy via JNK signaling, and promotes steroidogenesis in porcine granulosa cells

  7. SIRT1, p53 and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  8. porcine CD74 significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 may be implicated in the pathogenesis of PCV2 infection.

  9. These results suggest that trans-10, cis-12-conjugated linoleic acid can modulate TNF-alpha production and NF-kappa B expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

Mouse (Murine) Nuclear Factor kappa B (NFkB) interaction partners

  1. Parkin modulates the lysine 63 ubiquitination status of RIPK1 to promote the activation of NF-kappaB and MAPKs.

  2. Reduced susceptibility to diet-induced obesity and dyslipidemia in p50(-/-) mice results from an increase in metabolic rate.

  3. NF-kappaB participated in the hepatocellular carcinoma suppressor function of Ndrg2-deficient macrophages.

  4. TLR3-NFkappaB pathway is necessary for the maturation of committed precursors into mature cardiomyocytes.

  5. The findings of this study support that loss of NF-kappaB p50 function and aging in middle-aged mice may interact to excessively augment peripheral/microglial pro-inflammatory responses and point to a novel neuroinflammation signaling mechanism independent the NF-kappaB p50/p65 transcription factor in this process.

  6. NF-kappa B inhibition abrogates TLR4-promoted catabolic and inflammatory responses in high glucose-treated chondrocytes.

  7. the feedback loop of the "EMMPRIN/NF-kappaB" pathway plays an important role in atherosclerotic plaques via modulation of autophagy in macrophages.

  8. Studied effect of Papaver nudicaule extract on reduction of inflammation through inactivating NF-kappaB and signal transducer and activator of transcription 3 (STAT3) in lipopolysaccharide treated RAW264.7 cells.

  9. These results indicate the relevance of CX3CL1 in the activation of the pro-inflammatory NF-kappaB signalling pathway through MSK1 in microglial cells.

  10. Data show that MiR-199a could regulate the activation of NF-kappa B (NF-kappaB) by directly targeting Klotho protein.

  11. These results reveal the roles for NF-kappaB during different phases of neocortical gliogenesis and identify NF-kappaB as an inhibitor of early oligodendrocyte development in the cerebral cortex.

  12. NF-KB p50 involvement in colorectal cancer development, through its engagement in the protumor activation of macrophages, identifies it as a candidate for prognostic and target therapeutic intervention.

  13. MicroRNA-326 aggravates acute lung injury in septic shock by mediating the NF-kappaB signaling pathway via BCL2A1.

  14. High NFKB1expression is associated with Osteoarthritis.

  15. Reducing NF-kappaB activation attenuates PDLIM2 deficiency-exacerbated inflammation and dyslipidemia in Palmitate -treated primary hepatocytes.

  16. Findings confirm that signalling through MyD88 is the primary driver for Lipopolysaccharide-dependent NF-kappaB translocation to the nucleus. The pattern of NF-kappaB dynamics in TRIF-deficient cells does not, however, directly reflect the kinetics of TNFalpha promoter activation, supporting the concept that TRIF-dependent signalling plays an important role in the transcription of this cytokine.

  17. Chandipura virus infection triggered the activation of signalling pathways mediated by mitogen-activated protein kinases, including p38, JNK 1 and 2, and nuclear factor kappaB.

  18. These findings provide mechanistic insight into how polymorphisms that attenuate NFKB1 expression predispose humans to epithelial cancers, highlighting the pro-tumorigenic activity of STAT1 and identifying targetable vulnerabilities in GC.

  19. Macrophage-derived IL1B/NF-kappaB signaling mediates parenteral nutrition-associated cholestasis in a mouse model.

  20. SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF-kappaB pathway in mouse Kupffer cells.

Nuclear Factor kappa B (NFkB) Antigen Profile

Protein Summary

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NFkB

  • nuclear factor kappa B subunit 1 (NFKB1) antibody
  • nuclear factor kappa B subunit 1 (Nfkb1) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1) antibody
  • EBP-1 antibody
  • KBF1 antibody
  • NF-kappa-B antibody
  • NF-kappaB antibody
  • NF-kappaB1 antibody
  • NF-kB antibody
  • NF-KB1 antibody
  • NFkappaB antibody
  • NFKB-p50 antibody
  • NFKB-p105 antibody
  • p50 antibody
  • p50/p105 antibody
  • p105 antibody

Protein level used designations for NFkB

DNA binding factor KBF1 , DNA-binding factor KBF1 , NF-kappabeta , nuclear factor NF-kappa-B p105 subunit , nuclear factor NF-kappa-B p50 subunit , nuclear factor kappa-B DNA binding subunit , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , NF-kB p50 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) , nuclear factor kappa-B 1 , EBP-1 , NF kappaB1 , NF-kappa-B1 p84/NF-kappa-B1 p98 , NF-kappaB p50 , nuclear factor kappaB p50 , nuclear factor-kappaB p50 , p50 subunit of NF kappaB , p50 subunit of NF-kappaB

4790 Homo sapiens
81736 Rattus norvegicus
396033 Gallus gallus
442859 Canis lupus familiaris
751869 Sus scrofa
18033 Mus musculus
100730075 Cavia porcellus
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