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Negative regulator of sphingolipid synthesis (By similarity). Additionally we are shipping and many more products for this protein.
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ORMDL1 downregulation modestly increased levels of sphingosine, S1P (show MBTPS1 Antibodies), and ceramide in HepG2 cells.
ORMDL1, ORMDL2 (show ORMDL2 Antibodies) and ORMDL3 (show ORMDL3 Antibodies) mediate the feedback response in ceramide biosynthesis.
Adoplin-1/ORMDL-1 displays reduced expression in association with presenilin mutations; Adoplin-1 & two highly homologous genes (adoplin-2 (show ORMDL2 Antibodies), -3) are a gene family that encodes transmembrane proteins that may play roles in gamma-secretase complex maturation
free-cholesterol accumulation diminishes ORMDL1 expression
Negative regulator of sphingolipid synthesis (By similarity).
ORM1-like protein 1
, uncharacterized protein LOC100188936