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RPAP3 encodes an RNA polymerase II-associated protein. Additionally we are shipping RPAP3 Proteins (4) and and many more products for this protein.
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RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
this study investigated the interaction between RPAP3 and PIH1D1.
These results indicate that RPAP3 may be a novel modulator of NF-kappaB pathway in apoptosis induced by anti-cancer chemotherapeutic agents.
Data indicate that RNA polymerase II is built in the cytoplasm and reveal quality-control mechanisms that link HSP90 and its cochaperone hSpagh (RPAP3) to the nuclear import of fully assembled enzymes.
Overexpression of RPAP3 in HEK 293 cells potentiated caspase-3 activation and apoptosis.
RPAP3 interacts with Reptin to modulate UV-induced DNA damage by regulating H2AX phosphorylation
Is part of an RNA polymerase II-associated complex with possible chaperone activity.
This gene encodes an RNA polymerase II-associated protein. The encoded protein may function in transcriptional regulation and may also regulate apoptosis. Alternatively spliced transcript variants have been described.
RNA polymerase II-associated protein 3
, RNA polymerase II associated protein 3