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The function of RASSF4 has not yet been determined but may involve a role in tumor suppression.
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RASSF4 (show RIN2 Proteins) controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6 (show ARF6 Proteins)-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes.
RASSF4 (show RIN2 Proteins) overexpression inhibits proliferation, invasion, EMT (show ITK Proteins), and Wnt (show WNT2 Proteins) signaling pathway in osteosarcoma cells.
the present study suggested that RASSF4 (show RIN2 Proteins) serves as an important tumor suppressor in human nonsmall cell lung cancer .
RASSF4 (show RIN2 Proteins) promotes EV71 replication and the production of viral progeny to accelerate the inhibition of the phosphorylation of AKT (show AKT1 Proteins).
expression of SPRR1B (show SPRR1B Proteins) is upregulated in oral CSCs/CICs and SPRR1B (show SPRR1B Proteins) has a role in cell growth by suppression of RASSF4 (show RIN2 Proteins)
Single nucleotide polymorphism in RASSF4 (show RIN2 Proteins) gene is associated with acute lymphoblastic leukemia.
The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants\; however, most of the variants have not been fully described.
Ras association (RalGDS/AF-6) domain family 4
, Ras association domain family 4
, ras association domain-containing protein 4
, tumor suppressor RASSF4
, Ras association (RalGDS/AF-6) domain family member 4