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The protein encoded by STK35 is a kinase that is predominantly found in the nucleus.
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Human Polyclonal STK35 Primary Antibody for IHC, ELISA - ABIN185178
Vallenius, Mäkelä: Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein. in Journal of cell science 2002
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STK35 knockdown enhanced apoptosis. Expression of the active forms and the activity of two major executioner caspases, caspase 3 (show CASP3 Antibodies) and caspase 7 (show CASP7 Antibodies), were also increased in osteosarcoma cells with STK35 silenced.
constitutive overexpression of STK35 proteins enhances caspase (show CASP3 Antibodies)-independent cell death under oxidative stress conditions.
by regulating CDKN2A and inhibiting G1- to S-phase transition STK35L1 may act as a central kinase linking the cell cycle and migration of endothelial cells
analysis of the STK35L proteins in human and in sea (show Slc25a1 Antibodies) squirts
results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers
The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells.
serine/threonine kinase 35
, Serine/threonine-protein kinase 35
, CLP-36 interacting kinase
, CLP-36-interacting kinase 1
, PDLIM1-interacting kinase 1
, serine threonine kinase 35 long form
, serine/threonine-protein kinase 35
, serine/threonine-protein kinase 35 L1