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SIGLEC8 Proteins

(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM\\\\; MIM 603492) that mediates an association with SLAM-associated protein (SAP\\\\; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010].
SIGLEC8 Protein (AA 17-363) (Fc Tag) SIGLEC8 Protein (AA 17-363) (Fc Tag) SIGLEC8 Protein (AA 17-363) (Fc Tag) (ABIN7275591)

SIGLEC8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

SIGLEC8 Protein (AA 18-121) (GST tag) SIGLEC8 Protein (AA 18-121) (GST tag) SIGLEC8 Protein (AA 18-121) (GST tag) (ABIN1320000)

SIGLEC8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SIGLEC8 Protein (AA 17-363) (His-Avi Tag) SIGLEC8 Protein (AA 17-363) (His-Avi Tag) SIGLEC8 Protein (AA 17-363) (His-Avi Tag) (ABIN7275601)

SIGLEC8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

SIGLEC8 Proteins by Grade

Find SIGLEC8 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SIGLEC8 Proteins by Origin

Find SIGLEC8 Proteins for a variety of species such as anti-Human SIGLEC8. The species listed below are among those available. Click on a link to go to the corresponding products.

SIGLEC8 Proteins by Source

Here you will find SIGLEC8 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SIGLEC8 Proteins by Protein Type

Here you can find SIGLEC8 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SIGLEC8 Proteins by Application

Find SIGLEC8 Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SIGLEC8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275591
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320000
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7275601
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7319860
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7319841
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7275602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3076984
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3076983
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3118650
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394819
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330477
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6938866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713656
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our SIGLEC8 Proteins

von Gunten, Vogel, Schaub, Stadler, Miescher, Crocker, Simon: "Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies." in: The Journal of allergy and clinical immunology, Vol. 119, Issue 4, pp. 1005-11, (2007) (PubMed).

Aliases for SIGLEC8 Proteins

sialic acid binding Ig like lectin 8 (SIGLEC8) Proteins
sialic acid-binding Ig-like lectin 8 (LOC506364) Proteins
SAF2 Proteins
SIGLEC-8 Proteins
SIGLEC8 Proteins
SIGLEC8L Proteins
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