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The protein encoded by SMO is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins.
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Human Polyclonal SMO Primary Antibody for IHC (p), WB - ABIN4354843
Walter, Omura, Hong, Griffith, Vincent, Borges, Goggins: Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010
Show all 4 Pubmed References
Human Polyclonal SMO Primary Antibody for ELISA, WB - ABIN188668
Corbit, Aanstad, Singla, Norman, Stainier, Reiter: Vertebrate Smoothened functions at the primary cilium. in Nature 2005
Human Polyclonal SMO Primary Antibody for ELISA, WB - ABIN188673
Taipale, Cooper, Maiti, Beachy: Patched acts catalytically to suppress the activity of Smoothened. in Nature 2002
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
, smoothened, frizzled family receptor
, smoothened, seven transmembrane spanning receptor