anti-Synuclein, beta (SNCB) Antibodies

The protein encoded by SNCB is highly homologous to alpha-synuclein. Additionally we are shipping beta Synuclein Proteins (16) and beta Synuclein Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNCB 6620 Q16143
SNCB 104069 Q91ZZ3
SNCB 113893 Q63754
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Top anti-beta Synuclein Antibodies at

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Beta-synuclein staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Beta-synuclein expression in HeLa (A), human brain (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using Synuclein beta Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synuclein beta Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB SNCB Antibody (C-term) (ABIN652024) western blot analysis in mouse cerebellum tissue lysates (15 µg/lane). This demonstrates the SNCB antibody detected SNCB protein (arrow). SNCB antibody(C-term) (ABIN652024) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Anti-SNCB / Beta-Synuclein antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104401 concentration 10 ug/ml. 50 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti Beta-synuclein/SNCB Polyclonal Antibody, Unconjugated (ABIN1387731) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
Human Mouse Un-conjugated WB Western Blot analysis of SNCB expression in transfected 293T cell line by SNCB monoclonal antibody (M07), clone 3H4. Lane 1: SNCB transfected lysate(14.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 50 μg Log in to see 12 to 14 Days

SNCB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine)
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Rat (Rattus) , ,

More Antibodies against beta Synuclein Interaction Partners

Human Synuclein, beta (SNCB) interaction partners

  1. Data suggest that pH serves as an on/off switch for beta- synuclein to form aggregates/fibrils (as seem in Parkinson disease); hydrogen bonding between glutamate (show GRIN1 Antibodies) residues appears to be involved in fibril formation.

  2. loss of inhibitory C-terminal conformations in disease associated P123H beta-synuclein

  3. beta-Synuclein expression was locally concentrated and rather modest, but nevertheless changed its effect on amyloid precursor protein (show APP Antibodies) expression and plaque load in a time- and concentration-dependent manner.

  4. The differing aggregation propensities of alpha-synuclein and beta-synuclein are associated with differences in the degree of residual structure in the C-terminus coupled to the shorter separation between the N- and C-termini in beta-synuclein.

  5. Beta-synuclein protects against isoaspartate accumulation in alpha-synuclein.

  6. In vivo cross-linking reveals principally oligomeric forms of alpha-synuclein and beta-synuclein in neurons and non-neural cells

  7. Thermodynamic studies in conjunction with EPR confirm that alpha-synuclein, beta-synuclein, and gamma-synuclein bind copper(II) in a high affinity 1:1 stoichiometry.

  8. Data provide evidence for the role of beta-synuclein minor transcript variants in the development of complex diseases and provide new insights into the pathogenesis of Lewy body diseases.

  9. This study suggested that the pathogenesis of dementia in Parkinson disease, indicating that differential sncb expression in the caudate nucleus may represent one of the molecular mechanisms involved in these complex diseases.

  10. Despite both synucleins sharing considerable sequence homology, the level of carboxy-terminal Src kinase-homologous kinase (CHK) phosphorylation of beta-synuclein is significantly higher than that of alpha-synuclein.

Mouse (Murine) Synuclein, beta (SNCB) interaction partners

  1. Immunoblot analysis of beta-synuclein and Akt (show AKT1 Antibodies) levels in the mice reveals selective increases in beta-synuclein and phosphorylated Akt (show AKT1 Antibodies) levels in ventral midbrain

  2. Beta-synuclein decreased formation of Lewy bodies by 40%, and prevented functional deficits associated with overexpression of alpha-synuclein. This is a preliminary in vivo proof of antiaggregatory function of beta-synuclein.

  3. Accelerated accumulation of beta-synuclein is found in axonal spheroids of gracile axonal dystrophy mice, which do not express ubiquitin carboxyl-terminal hydrolase L1.

  4. beta-synuclein knockout mice show that synucleins are not essential components of the basic machinery for neurotransmitter release but may contribute to the long-term regulation and/or maintenance of presynaptic function.

  5. Developmentally, gamma-synuclein (show SNCG Antibodies) can be seen in the region of the outer hair cells by E19, while alpha- and beta-synuclein do not clearly appear there until approximately P10 (show NUTF2 Antibodies)

Zebrafish Synuclein, beta (SNCB) interaction partners

  1. Data show the sequences of zebrafish synucleins are very similar to those of the human proteins. Whole-mount in situ hybridization show that sncb were expressed strongly in the nervous system.

beta Synuclein (SNCB) Antigen Profile

Protein Summary

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease\; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Synuclein, beta (SNCB) Antibodies

  • synuclein beta (SNCB) antibody
  • synuclein, beta (Sncb) antibody
  • synuclein, beta (sncb) antibody
  • synuclein beta (sncb) antibody
  • synuclein beta L homeolog (sncb.L) antibody
  • Beta-synuclein (syub) antibody
  • AI838531 antibody
  • betaSYN antibody
  • LOC619281 antibody
  • MGC75784 antibody
  • SNCB antibody
  • syub antibody
  • zgc:66343 antibody

Protein level used designations for anti-Synuclein, beta (SNCB) Antibodies

beta-synuclein , PNP 14 , phosphoneuroprotein 14 , zSyn-&beta , zSynC , synuclein, beta , putative beta-synuclein variant 1 , Beta-synuclein

6620 Homo sapiens
104069 Mus musculus
113893 Rattus norvegicus
393944 Danio rerio
394467 Xenopus (Silurana) tropicalis
395391 Gallus gallus
479279 Canis lupus familiaris
495448 Xenopus laevis
508421 Bos taurus
619281 Takifugu rubripes
697484 Macaca mulatta
736255 Pan troglodytes
100127169 Sus scrofa
100190189 Taeniopygia guttata
100196630 Salmo salar
100354265 Oryctolagus cuniculus
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