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TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1\\\\; MIM 164011) (Matsumura et al., 2004 [PubMed 15047173]).[supplied by OMIM, Mar 2009].. Additionally we are shipping TRAF-Interacting Protein with Forkhead-Associated Domain, Family Member B Proteins (3) and many more products for this protein.
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TIFAB loss increases TRAF6 (show TRAF6 Antibodies) protein and the dynamic range of TLR4 (show TLR4 Antibodies) signaling
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5 (show CXXC5 Antibodies), TIFAB and ETF1 (show ETF1 Antibodies), as well as the Wnt (show WNT2 Antibodies) pathway, as potential targets in del(5q) myeloid neoplasms
study shows TIFAB is mainly expressed in B cells rather than T cells in the spleen; results suggest TIFAB could act as a negative regulator of TRAF6 (show TRAF6 Antibodies)-induced cellular function such as B cell proliferation and maturation of dendritic cellss & macrophages
TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1\; MIM 164011) (Matsumura et al., 2004
TRAF-interacting protein with forkhead-associated domain, family member B
, TIFA-like protein
, TIFA-related protein TIFAB
, TRAF-interacting protein with FHA domain-containing protein B
, TIFA like protein
, TIFA related protein TIFAB