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Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Additionally we are shipping TEFM Kits (7) and TEFM Proteins (6) and many more products for this protein.
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Human Polyclonal TEFM Primary Antibody for ICC, IF - ABIN4358359
Posse, Shahzad, Falkenberg, Hällberg, Gustafsson: TEFM is a potent stimulator of mitochondrial transcription elongation in vitro. in Nucleic acids research 2015
Data provide insights into target specificity of TEFM and mechanisms by which it regulates the switch between transcription and replication of mitochondrial DNA.
Data indicate transcription elongation factor (show TSFM Antibodies) (TEFM) as an essential component of the mitochondrial transcription machinery.
study found interaction of TEFM with mitochondrial RNA polymerase and nascent transcript prevents generation of replication primers and increases transcription processivity and serves as a molecular switch between replication and transcription, which appear to be mutually exclusive processes in mitochondria
The TEFM protein is proposed to be a critical component of the transcription apparatus of human mitochondria.
Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
transcription elongation factor of mitochondria
, transcription elongation factor, mitochondrial