Transient Receptor Potential Cation Channel, Subfamily M, Member 3 Proteins (TRPM3)

The product of TRPM3 belongs to the family of transient receptor potential (TRP) channels. Additionally we are shipping TRPM3 Antibodies (51) and TRPM3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPM3 80036 Q9HCF6
Mouse TRPM3 TRPM3 226025  
Rat TRPM3 TRPM3 309407  
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Top TRPM3 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
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Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Log in to see 11 Days
$411.40
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TRPM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3) Interaction Partners

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3) interaction partners

  1. TRPM3 activity is impaired in Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) patients suggesting changes in intracellular Ca2+ concentration, which may impact NK cellular functions. This investigation further helps to understand the intracellular-mediated roles in NK cells and confirm the potential role of TRPM3 ion channels in the aetiology and pathomechanism of CFS/ME.

  2. Genetic experiments revealed that the basic region leucine zipper proteins c-Jun and ATF2 and the ternary complex factor Elk-1 are essential to couple TRPM3 channel stimulation with the IL-8 gene.

  3. this study shows that differential expression of TRPM3 and Ca2+ flux between NK cell subtypes may provide evidence for their role in the pathomechanism involving NK cell cytotoxicity activity in chronic fatigue syndrome/myalgic encephalomyelitis

  4. rs10780946 TRPM3 polymorphism is associated with asthma-exacerbated respiratory disease susceptibility.

  5. Phosphoinositols regulate TRPM3.

  6. Activation of TRPM3 channels increases the transcriptional activation potential of c-Fos in HEK293 cells.

  7. This is the first study to examine the involvement of TRPM channel gene variations on the risk of SSc incidence. Our results suggest roles of TRPM3 and TRPM5 gene variants in the susceptibility to or clinical expression of Systemic sclerosis

  8. The TRPM3 activity is rapidly and reversibly inhibited by activation of phosphatases.

  9. TRPM3 is a phosphoinositide-dependent ion channel.

  10. Missense mutation in the cation channel, TRPM3, underlies inherited cataract and glaucoma.

  11. TRPM3 channel activation changes the gene expression pattern of the cells by activating transcription of c-Jun-, ATF2-, and TCF-controlled genes.

  12. The von Hippel-Lindau tumor suppressor (VHL) represses TRPM3 directly through miR-204 and indirectly through another miR-204 target, Caveolin 1.

  13. Pregnenolone sulfate is a powerful activator of TRPM3-mediated gene transcription, while transcription is completely inhibited by mefenamic acid in cells expressing activated TRPM3 channels.

  14. Data using recombinant proteins expressed in vascular endothelial cells suggest that SigmaR1 (sigma 1-type opioid receptor) is not involved in regulation of calcium signaling via TRPC5/TRPM3 (transient receptor potential cation channels C5/M3).

  15. TRPM3-ICF deletion mutation variants are regulatory channel subunits fine-tuning TRPM3 channel activity.

  16. Progesterone (0.01-10muM) suppressed TRPM3 activity evoked by pregnenolone sulphate.

  17. Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel.

  18. The inhibition of TRPM1 by zinc ions is primarily due to a short stretch of seven amino acids present only in the pore region of TRPM1 but not of TRPM3.

  19. Our data establish that TRPM3 channels constitute a regulated entry pathway for zinc ions in pancreatic beta-cells

  20. data suggest functional relevance of TRPM3 in contractile and proliferating phenotypes of vascular smooth muscle cells

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3) interaction partners

  1. findings indicate that the initiation of the acute heat-evoked pain response in sensory nerve endings relies on three functionally redundant TRP channels, representing a fault-tolerant mechanism to avoid burn injury

  2. Primary cilia are required for the maximal osmotic response in renal epithelial cells and TRPM3 is involved in this osmoregulatory mechanism.

  3. TRPM3 activation in sensory nerve endings can contribute to neurogenic inflammation.

  4. transcriptional control of Trpm3/miR-204 is reported.

  5. data support an indirect role for TRPM3 in pupillary light responses

  6. These experiments reveal an unanticipated role for TRPM3 as a thermosensitive nociceptor channel implicated in the detection of noxious heat.

  7. Signal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factors.

  8. data suggest functional relevance of TRPM3 in contractile and proliferating phenotypes of vascular smooth muscle cells

  9. These results demonstrate that TRB3 induction is a significant aspect of the ER stress response in cardiac myocytes and that TRB3 antagonizes cardiac glucose metabolism and cardiac myocyte survival.

  10. the divalent cation selectivity of TRPM3 channels is regulated by altenrative splicing

  11. TRPM3 is an essential component of an ionotropic steroid receptor enabling unanticipated crosstalk between steroidal and insulin-signalling endocrine systems.

TRPM3 Protein Profile

Protein Summary

The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with TRPM3

  • transient receptor potential cation channel subfamily M member 3 (TRPM3)
  • transient receptor potential cation channel, subfamily M, member 3 (Trpm3)
  • transient receptor potential cation channel, subfamily M, member 3 (trpm3)
  • transient receptor potential cation channel, subfamily M, member 3 (TRPM3)
  • 6330504P12Rik protein
  • 9330180E14 protein
  • AU018608 protein
  • B930001P07Rik protein
  • GON-2 protein
  • LTRPC3 protein
  • MLSN2 protein
  • si:dkey-201c13.4 protein
  • trpm6 protein

Protein level used designations for TRPM3

LTrpC-3 , long transient receptor potential channel 3 , melastatin 2 , melastatin-2 , transient receptor potential cation channel subfamily M member 3 , transient receptor potential melastatin 3 beta 1 , transient receptor potential melastatin 3 beta 10 , transient receptor potential melastatin 3 beta 11 , transient receptor potential melastatin 3 beta 12 , transient receptor potential melastatin 3 beta 13 , transient receptor potential melastatin 3 beta 15 , transient receptor potential melastatin 3 beta 16 , transient receptor potential melastatin 3 beta 17 , transient receptor potential melastatin 3 beta 2 , transient receptor potential melastatin 3 beta 3 , transient receptor potential melastatin 3 beta 4 , transient receptor potential melastatin 3 beta 5 , transient receptor potential melastatin 3 beta 6 , transient receptor potential melastatin 3 beta 7 , transient receptor potential melastatin 3 beta 8 , transient receptor potential melastatin 3 beta 9 , transient receptor potential cation channel, subfamily M, member 6

GENE ID SPECIES
80036 Homo sapiens
226025 Mus musculus
565807 Danio rerio
540699 Bos taurus
309407 Rattus norvegicus
476326 Canis lupus familiaris
100157158 Sus scrofa
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