Twisted Gastrulation Homolog 1 Proteins
(Twisted Gastrulation Homolog 1 (TWSG1))
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
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13 results
TWSG1
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
TWSG1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 93 % as determined by SDS-PAGE
1 image
TWSG1
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
TWSG1
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
TWSG1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, ELISA, SDS
TWSG1
Origin: Human
Host: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, ELISA, SDS, Imm, AcA
Active
TWSG1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
TWSG1
Origin: Zebrafish (Danio rerio)
Host: Yeast
Recombinant
> 90 %
ELISA
TWSG1
Origin: Xenopus laevis
Host: Yeast
Recombinant
> 90 %
ELISA
TWSG1
Origin: Xenopus laevis
Host: Yeast
Recombinant
> 90 %
ELISA
TWSG1
Origin: Zebrafish (Danio rerio)
Host: Yeast
Recombinant
> 90 %
ELISA
Latest Publications for our Twisted Gastrulation Homolog 1 Proteins
: "High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin." in: Nature medicine, Vol. 13, Issue 9, pp. 1096-101, (2007) (PubMed).Aliases for Twisted Gastrulation Homolog 1 Proteins
twisted gastrulation BMP signaling modulator 1 (TWSG1) Proteinstwisted gastrulation homolog 1 (Drosophila) (TWSG1) Proteins
twisted gastrulation BMP signaling modulator 1 (Twsg1) Proteins
twisted gastrulation BMP signaling modulator 1a (twsg1a) Proteins
twisted gastrulation BMP signaling modulator 1 S homeolog (twsg1.S) Proteins
twisted gastrulation BMP signaling modulator 1 L homeolog (twsg1.L) Proteins
twisted gastrulation BMP signaling modulator 1b (twsg1b) Proteins
1810013J15Rik Proteins
9030422N06Rik Proteins
AW552143 Proteins
D17Ertd403e Proteins
DKFZp469J051 Proteins
fi23f01 Proteins
TSG Proteins
Tsg Proteins
tsg Proteins
tsg1 Proteins
tsga Proteins
tsgb Proteins
Twg Proteins
twsg Proteins
TWSG1 Proteins
twsg1 Proteins
wu:fi23f01 Proteins
ztsg1 Proteins
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