anti-Mouse (Murine) NANOS3 antibody for Enzyme Immunoassay

Recommended NANOS3 Antibody (supplied by: Log in to see )

Antigen
Nanos Homolog 3 (NANOS3) Antibodies
  • NANOS1L
  • NOS3
  • nos3
  • cb725
  • nanos
  • nanos1
  • nos1
  • nanos C2HC-type zinc finger 3
  • nanos homolog 3 (Drosophila)
  • nanos homolog 3
  • NANOS3
  • Nanos3
  • nanos3
Epitope
C-Term
11
4
3
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
32
14
13
Host
Rabbit
31
1
Clonality
Polyclonal
Conjugate
This NANOS3 antibody is un-conjugated
4
4
3
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
27
22
8
6
2
1
1
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Catalog No. ABIN5555038
$ 474.10
Plus shipping costs $45.00

General

Antigen Nanos Homolog 3 (NANOS3) Antibodies
Epitope C-Term
(11), (4), (3), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(32), (14), (13)
Host Rabbit
(31), (1)
Clonality
Polyclonal
Conjugate This NANOS3 antibody is un-conjugated
(4), (4), (3)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(27), (22), (8), (6), (2), (1), (1)
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Product Details anti-NANOS3 Antibody

Target Details NANOS3 Application Details Handling Images
Specificity This antibody detects Nanos3 at C-term. It will not cross-react with either Nanos 1 or Nanos2.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogen Nanos3 antibody was raised against a 16 amino acid peptide near the carboxy terminus of the human Nanos3.
Isotype IgG
Plasmids, Primers & others

Target Details NANOS3

Product Details anti-NANOS3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name NANOS3 (NANOS3 Antibody Abstract)
Background Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.Synonyms: MGC120114, NANOS1L, NOS3, Nanos homolog 3
Gene ID 342977
NCBI Accession NP_001092092
UniProt Q495E5
Pathways ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling

Application Details

Product Details anti-NANOS3 Antibody Target Details NANOS3 Handling Images back to top
Application Notes ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NANOS3 Antibody Target Details NANOS3 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.