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AGO2 Products

(Argonaute 2 (AGO2))
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Featured AGO2 Categories

AGO2 Antibodies

High quality antibodies with extensive validation data.

AGO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

AGO2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AGO2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
Validations
  • (44)
  • (7)
Cat. No. ABIN565346
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ChIP
Validations
  • (5)
Cat. No. ABIN7165091
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN7261908
Quantity 200 μL
Datasheet Datasheet

Recommended AGO2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975055
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975511
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1150589
Quantity 96 tests
Datasheet Datasheet

Recommended AGO2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352528
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320195
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7194308
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AGO2 products

Li, Yin, Bao, Liu: "Targeting a novel circITCH/miR-421/BTG1 axis is effective to suppress the malignant phenotypes in hepatocellular carcinoma (HCC) cells." in: Cytotechnology, Vol. 75, Issue 3, pp. 255-267, (2023) (PubMed).

Reed, Westergreen, Barajas, Ressler, Phuong, Swain, Lingappa, Lingappa: "Formation of RNA Granule-Derived Capsid Assembly Intermediates Appears To Be Conserved between Human Immunodeficiency Virus Type 1 and the Nonprimate Lentivirus Feline Immunodeficiency Virus." in: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).

Mantel, Hjelmqvist, Walch, Kharoubi-Hess, Nilsson, Ravel, Ribeiro, Grüring, Ma, Padmanabhan, Trachtenberg, Ankarklev, Brancucci, Huttenhower, Duraisingh, Ghiran, Kuo, Filgueira, Martinelli, Marti: "Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria." in: Nature communications, Vol. 7, pp. 12727, (2016) (PubMed).

Wang, Ye, Wei, Han, He, Chen, Chen: "LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 117, (2016) (PubMed).

Xiao, Wang, Ni, Li, Zhang, Liu, Pu, Xu, Gao, Zhao, Mu, Wang, Sun, Du, Xu, Zhang, Hiscox, Goodfellow, Zhou: "MicroRNA miR-24-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication through Suppression of Heme Oxygenase-1 Expression." in: Journal of virology, Vol. 89, Issue 8, pp. 4494-503, (2015) (PubMed).

Bernard, Wang, Tachado: "DICER-ARGONAUTE2 complex in continuous fluorogenic assays of RNA interference enzymes." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120614, (2015) (PubMed).

Zhang, Guo, Gao, Huang, Li, Jia, Liu, Feng: "MicroRNA-23 inhibits PRRSV replication by directly targeting PRRSV RNA and possibly by upregulating type I interferons." in: Virology, Vol. 450-451, pp. 182-95, (2014) (PubMed).

Nakanishi, Taccioli, Palatini, Fernandez-Cymering, Cui, Kim, Volinia, Croce: "Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway." in: Oncogene, Vol. 33, Issue 6, pp. 702-12, (2014) (PubMed).

Sasaki, Gross, Xing, Goshima, Bassell: "Identification of axon-enriched microRNAs localized to growth cones of cortical neurons." in: Developmental neurobiology, Vol. 74, Issue 3, pp. 397-406, (2014) (PubMed).

Pai, Siripornmongcolchai, Berentsen, Pakzad, Vieuille, Pallesen, Pajak, Simpson, Armstrong, Wibrand, Bramham: "NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo." in: Frontiers in cellular neuroscience, Vol. 7, pp. 285, (2014) (PubMed).

Synonyms and alternative names related to AGO2

argonaute 2, RISC catalytic component (AGO2), Argonaute family protein (AGO2), argonaute 2, RISC catalytic component (Ago2), argonaute 2, RISC catalytic component L homeolog (ago2.L), argonaute RISC catalytic subunit 2 (Ago2), argonaute RISC catalytic component 2 (AGO2), Argonaute 2 (AGO2), argonaute 2, RISC catalytic component (ago2), 1110029L17Rik, 2310051F07Rik, AG02, ago, Ago-2, ago-2, AGO2, AGO 2, Ago2, ago2, AI225898, AL022874, argonaute 2, Argonaute2, AW546247, CG7439, CG13452, dAGO2, dAgo2, Dm Ago2, Dmel\\CG7439, eif2c1, EIF2C2, Eif2c2, eif2c2, eIF2C2, ENSMUSG00000072493, Gerp95, Gm10365, mKIAA4215, Q10, T19E23.7, T19E23_7

Protein level used designations for AGO2

  • eukaryotic translation initiation factor 2C, 2
  • protein argonaute-2-like
  • PAZ Piwi domain protein
  • PPD
  • argonaute 2
  • argonaute2
  • eIF-2C 2
  • eIF2C 2
  • hAgo2
  • protein argonaute-2
  • protein slicer
  • GERp95
  • golgi ER protein 95 kDa
  • Protein slicer
  • eukaryotic translation initiation factor 2C, 1
  • Piwi/Argonaute family protein meIF2C2
  • argonaute RISC catalytic component 2
  • mAgo2
  • eukaryotic translation initiation factor 2C 2
  • Eukaryotic translation initiation factor 2C 2
  • translation initiation factor eIF2C
  • AGO2-PB
  • AGO2-PC
  • AGO2-PE
  • ARGONAUTE2
  • CG7439-PB
  • CG7439-PC
  • CG7439-PE
  • argonaute
  • argonaute-2
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