ACSL1 antibody
-
- Target See all ACSL1 (Acsl1) Antibodies
- ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ACSL1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificity
- At least three isoforms of ACSL1 are known to exist, this antibody will detect all three isoforms.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal ACSL1 antibody was raised against an 18 amino acid peptide near the center of human ACSL1.
- Isotype
- IgG
- Top Product
- Discover our top product Acsl1 Primary Antibody
-
-
- Application Notes
- ACSL1 antibody can be used for detection of ACSL1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- Comment
-
(IN) Acyl-CoA synthetase long-chain family member 1
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
- Storage Comment
- ACSL1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
-
- Target
- ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))
- Alternative Name
- ACSL1 (Acsl1 Products)
- Synonyms
- ACS1 antibody, FACL1 antibody, FACL2 antibody, LACS antibody, LACS1 antibody, LACS2 antibody, Acas antibody, Acas1 antibody, Acs antibody, FACS antibody, Facl2 antibody, ACS antibody, COAA antibody, zgc:110081 antibody, CER8 antibody, ECERIFERUM 8 antibody, LONG-CHAIN ACYL-COA SYNTHASE 1 antibody, T8I13.8 antibody, F13F21.14 antibody, F13F21_14 antibody, LATERAL ROOT DEVELOPMENT 2 antibody, LRD2 antibody, long-chain acyl-CoA synthetase 2 antibody, acyl-CoA synthetase long chain family member 1 antibody, acyl-CoA synthetase long-chain family member 1 antibody, acyl-CoA synthetase long chain family member 1a antibody, AMP-dependent synthetase and ligase family protein antibody, long-chain acyl-CoA synthetase 2 antibody, ACSL1 antibody, Acsl1 antibody, acsl1a antibody, LACS1 antibody, LACS2 antibody
- Background
-
Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ASCL1 is the major acyl-CoA enzyme in the heart, providing 60-90% of heart ATP. Loss of ASCL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.
Synonyms: Acyl-CoA synthetase long-chain family member 1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2, palmitoyl-CoA ligase 1 - Molecular Weight
- 77 kDa
- Gene ID
- 2180
- NCBI Accession
- NP_001986
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
-