ACVR1 antibody (AA 147-161)

Catalog No. ABIN1099812

Product Details anti-ACVR1 Antibody

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Binding Specificity: AA 147-161

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Pig, Monkey, Bat

Host: Goat

Clonality: Polyclonal

Conjugate: This ACVR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human ACVR1 / ALK2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig (100%) Hamster (93%) Opossum (87%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-RKFKRRNQERLNPRD from an internal region of human ACVR1 / ALK2 (NP_001096.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig (100%), Hamster (93%), Opossum (87%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (4 μg/mL), Peptide-ELISA (1:128000), WB (0.3 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 4 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Alternative Name: ALK2 / ACVR1 (ACRV1 Products)

Synonyms: ACTRI antibody, ACVR1A antibody, ACVRLK2 antibody, ALK2 antibody, FOP antibody, SKR1 antibody, TSRI antibody, ActR-IA antibody, ActR-I antibody, ActRIA antibody, Acvr antibody, Acvrlk2 antibody, Alk-2 antibody, Alk8 antibody, D330013D15Rik antibody, Tsk7L antibody, actri antibody, acvr1 antibody, acvr1-a antibody, acvr1-b antibody, acvr1a antibody, acvrlk2 antibody, alk-2 antibody, alk2 antibody, alk8 antibody, fop antibody, sax antibody, skr1 antibody, tsri antibody, xALK-2 antibody, activin A receptor type 1 antibody, activin A receptor, type 1 antibody, activin A receptor type 1 S homeolog antibody, ACVR1 antibody, Acvr1 antibody, acvr1.S antibody

Background: Name/Gene ID: ACVR1
Subfamily: Activin/TGFb
Family: Protein Kinase

Synonyms: ACVR1, Activin A receptor type I, Activin A receptor, type I, ACTR-I, ActRIA, ACVR1A, ALK2, Activin receptor-like kinase 2, Activin receptor type-1, ACTRI, ACVRLK2, ALK-2, Activin receptor type I, Actr1, FOP, Hydroxyalkyl-protein kinase, SKR1, TSRI, TSR-I, Tsk7L

Gene ID: 90

NCBI Accession: NP_001096

UniProt: Q04771