Muscarinic Acetylcholine Receptor M2 antibody (AA 352-364)

Catalog No. ABIN1100800

Product Details anti-Muscarinic Acetylcholine Receptor M2 Antibody

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Binding Specificity: AA 352-364

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Guinea Pig, Sheep, Rabbit, Hamster, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human CHRM2. Reported variants represent identical protein: NP_001006628.1, NP_001006633.1, NP_001006627.1, NP_000730.1, NP_001006629.1, NP_001006630.1, NP_001006631.1, NP_001006632.1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Porcine, Guinea pig (100%) Bat, Opossum, Lizard (92%) Turkey, Chicken (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QNGDEKQNIVARK from an internal region of human CHRM2 (NP_000730.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Porcine, Guinea pig (100%), Bat, Opossum, Lizard (92%), Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:128000), WB (0.5 - 2 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 50kD band observed in Mouse Brain lysates (calculated MW of 51.5kD according to Mouse NP_987076.2). Recommended concentration: 0.5-2 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Alternative Name: CHRM2 / M2 (CHRM2 Products)

Synonyms: HM2 antibody, AChR-M2 antibody, Chrm-2 antibody, M2 antibody, chrm2 antibody, Acm2 antibody, GPM2 antibody, cholinergic receptor muscarinic 2 antibody, cholinergic receptor, muscarinic 2, cardiac antibody, cholinergic receptor, muscarinic 2a antibody, cholinergic receptor, muscarinic 2 antibody, CHRM2 antibody, Chrm2 antibody, chrm2a antibody

Background: Name/Gene ID: CHRM2
Subfamily: Acetylcholine
Family: GPCR

Synonyms: CHRM2, 7TM receptor, HM2, M2 muscarinic receptor, M2-mAChR, Muscarinic receptor M2, Muscarinic M2 receptor

Gene ID: 1129

NCBI Accession: NP_000730

UniProt: P08172