Muscarinic Acetylcholine Receptor M2 antibody

Catalog No. ABIN7128939

Product Details anti-Muscarinic Acetylcholine Receptor M2 Antibody

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human CHRM2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:10-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Alternative Name: CHRM2 (CHRM2 Products)

Synonyms: HM2 antibody, AChR-M2 antibody, Chrm-2 antibody, M2 antibody, chrm2 antibody, Acm2 antibody, GPM2 antibody, cholinergic receptor muscarinic 2 antibody, cholinergic receptor, muscarinic 2, cardiac antibody, cholinergic receptor, muscarinic 2a antibody, cholinergic receptor, muscarinic 2 antibody, CHRM2 antibody, Chrm2 antibody, chrm2a antibody

Background:

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

Aliases: 7TM receptor antibody, Acetylcholine receptor, muscarinic, 2 antibody, AChR antibody, Acm2 antibody, ACM2_HUMAN antibody, Cholinergic receptor muscarinic 2 antibody, Cholinergic receptor, muscarinic 2, cardiac antibody, Cholinergic receptor, muscarinic 2, isoform a antibody, Cholinergic receptor, muscarinic 2a antibody, CHRM 2 antibody, CHRM2 antibody, chrm2a antibody, CM2 antibody, FLJ43243 antibody, HM 2 antibody, HM2 antibody, M2 antibody, M2 muscarinic receptor antibody, M2-mAChR antibody, MGC120006 antibody, MGC120007 antibody, Muscarinic acetylcholine receptor M2 antibody, Muscarinic M2 receptor antibody

UniProt: P08172