NRF2 antibody (AA 445-458)

Catalog No. ABIN1103329

Product Details anti-NRF2 Antibody

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Binding Specificity: AA 445-458

Reactivity: Human, Rat, Mouse, Dog, Cow, Hamster, Bat

Host: Goat

Clonality: Polyclonal

Conjugate: This NRF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human NRF2. This antibody is expected to recognize all reported isoforms (NP_006155.2, NP_001138884.1, NP_001138885.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Mouse, Rat, Dog, Bat, Bovine, Dolphin, Hamster, Panda, Porcine (100%) Marmoset, Elephant, Horse, Rabbit, Guinea pig (93%) Turkey, Chicken (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KHSSRLEAHLTRDE from an internal region of human NRF2 (NP_006155.2, NP_001138884.1, NP_001138885.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Mouse, Rat, Dog, Bat, Bovine, Dolphin, Hamster, Panda, Porcine (100%), Marmoset, Elephant, Horse, Rabbit, Guinea pig (93%), Turkey, Chicken (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:64000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 70kD band observed in Human Lung lysates (calculated MW of 67.8kD according to NP_006155.2). Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Alternative Name: NFE2L2 / NRF2 (NFE2L2 Products)

Synonyms: Nrf2 antibody, nfe2l2 antibody, wu:fc15g09 antibody, wu:fj67e03 antibody, NF-E2R2 antibody, NRF2 antibody, AI194320 antibody, nuclear factor, erythroid 2-like 2a antibody, nuclear factor, erythroid 2 like 2 S homeolog antibody, nuclear factor, erythroid 2 like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, nuclear factor, erythroid 2-like 2 antibody, nfe2l2a antibody, nfe2l2.S antibody, NFE2L2 antibody, Nfe2l2 antibody

Background: Name/Gene ID: NFE2L2

Synonyms: NFE2L2, NF-E2-related factor 2, NFE2-related factor 2, NRF2

Gene ID: 4780

NCBI Accession: NP_006155, NP_001138884, NP_001138885

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling