×
For best experience we recommend to activate Javascript in your browser.
Angiopoietin 2 antibody (C-Term)
ANGPT2
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Angiopoietin 2 Antibody
(hide)
Target
See all Angiopoietin 2 (ANGPT2) Antibodies
Angiopoietin 2 (ANGPT2)
Binding Specificity
All epitopes for Angiopoietin 2 antibodies
C-Term
Reactivity
All reactivities for Angiopoietin 2 antibodies
Human, Mouse, Rat
Host
All hosts for Angiopoietin 2 antibodies
Rabbit
Clonality
All clonalities for Angiopoietin 2 antibodies
Polyclonal
Conjugate
All conjugates for Angiopoietin 2 antibodies
This Angiopoietin 2 antibody is un-conjugated
Application
All applications for Angiopoietin 2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Sequence
Sequence is different from the related Mouse sequence by two amino acids.
Specificity
This antibody detects Angiopoietin-2 near C-term. No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (tested):Human, Mouse, Rat
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide corresponding to a sequence mapping near the C-terminal of Human Angiopoietin-2
Isotype
IgG
Top Product
Discover our top product ANGPT2 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Angiopoietin 2
(hide)
Target
Angiopoietin 2 (ANGPT2)
Alternative Name
Angiopoietin-2 (ANGPT2 Products )
Synonyms
AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
Background
Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.Synonyms: ANG-2, ANG2, ANGPT2
Gene ID
11601
NCBI Accession
NP_031452
UniProt
O35608
Pathways
RTK Signaling
Recently viewed
(hide)