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P-Selectin antibody (FITC)
SELP
Reactivity: Human, Monkey
FACS
Host: Mouse
Monoclonal
AK-6
FITC
Product Details anti-P-Selectin Antibody (FITC)
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Target
See all P-Selectin (SELP) Antibodies
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Reactivity
All reactivities for P-Selectin antibodies
Human, Monkey
Host
All hosts for P-Selectin antibodies
Mouse
Clonality
All clonalities for P-Selectin antibodies
Monoclonal
Conjugate
All conjugates for P-Selectin antibodies
This P-Selectin antibody is conjugated to FITC
Application
All applications for P-Selectin antibodies
Flow Cytometry (FACS)
Specificity
This antibody reacts with a 140 kDa antigen expressed on activated platelets and also on endothelial cells both of blood and lymph vessels.
Cross-Reactivity (Details)
Species reactivity (tested):Human and Rhesus Monkey.
Purification
Affinity Chromatography on Protein G
Immunogen
Human platelet membrane glycoproteins.
Clone
AK-6
Isotype
IgG1
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Alternatives
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP
Reactivity: Human, Mouse, Rat, Pig
WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, 0.09 % Sodium Azide, 1 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for P-Selectin
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Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Alternative Name
CD62P / P-Selectin (SELP Products )
Synonyms
PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
Background
CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
Gene ID
6403
NCBI Accession
NP_002996
UniProt
P16109
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