P-Selectin antibody (PE)

Catalog No. ABIN1106515

Product Details anti-P-Selectin Antibody (PE)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Selectin antibody is conjugated to PE

Application: Immunofluorescence (IF)

Specificity: The monoclonal antibody is directed against the CD62-antigen.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Absorption / Emission: 488 nm / 575 nm

Immunogen: Human platelets

Clone: CRC81

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0,9 % BSA

Handling Advice: DO NOT FREEZE! This product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P / P-Selectin (SELP Products)

Synonyms: PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody

Background: CD62, an integral membrane sialoglycoprotein 140 kD, also designated GMP-140 (granule membrane protein 140) or PADGEM, which is expressed in platelet alpha granules that are translocated to the platelet surface upon activation with strong agonists. A similar protein, present in endothelial cell Weibel-Palade bodies, is transiently expressed on the surface of activated endothelial cells and functions as adhesion molecule for granulocytes. The antibody does not interfere with the functional activity of CD62 as an adhesion receptor for neutrophils.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

Gene ID: 6403

NCBI Accession: NP_002996

UniProt: P16109