M-CSF/CSF1 antibody

Catalog No. ABIN1108090

Product Details anti-M-CSF/CSF1 Antibody

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This M-CSF/CSF1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody is specifically reactive to rhM-CSF. Does not cross react with BSA or other human cytokines tested such as IL-1β, IL-8, IL-16, EGF, G-CSFR, GM-CSF, MCP-1, MCP-3, TGF-β and TNF-α.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein G affinity purified

Immunogen: Purified recombinant human M-CSF (rhM-CSF)

Clone: 21

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Double distillated water is recommended to adjust the final concentration to 1.00 mg/mL.

Buffer: 0.01 M PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Alternative Name: Macrophage Colony Stimulating Factor (M-CSF) (CSF1 Products)

Synonyms: CSF-1 antibody, MCSF antibody, C87615 antibody, Csfm antibody, op antibody, csf1-1 antibody, zgc:172186 antibody, CSF1 antibody, csf1-2 antibody, zgc:158436 antibody, colony stimulating factor 1 antibody, colony stimulating factor 1 (macrophage) antibody, colony stimulating factor 1a (macrophage) antibody, macrophage colony-stimulating factor 1 antibody, macrophage colony stimulating factor antibody, colony stimulating factor 1b (macrophage) antibody, CSF1 antibody, Csf1 antibody, csf1a antibody, LOC396599 antibody, LOC100860895 antibody, csf1b antibody

Background: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1

Gene ID: 1435

NCBI Accession: NP_000748

UniProt: P09603

Pathways: RTK Signaling