TAPBP antibody (N-Term)

Catalog No. ABIN1109199

Product Details anti-TAPBP Antibody

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAPBP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKGLAKRPGA LLLRQGPGEP PPRPDLDPEL YLSVHDPAGA LQAAFRRYPR

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity column

Immunogen: Synthetic peptide directed towards the N-terminal of human TAPBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for TAPBP

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Alternative Name: Tapasin (TAPBP) (TAPBP Products)

Synonyms: SI:dZ179B20.1 antibody, SI:dZ179B20.3 antibody, SI:dZ179B20.7 antibody, mhc1uda antibody, mhc1ufa antibody, tpsn antibody, zgc:109814 antibody, tapbp antibody, TAPBP antibody, D17Wsu91e antibody, TPN antibody, NGS17 antibody, TAPA antibody, TPSN antibody, TAP binding protein (tapasin), tandem duplicate 1 antibody, TAP binding protein antibody, tapbp.1 antibody, tapbp antibody, TAPBP antibody, Tapbp antibody

Background: TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.Synonyms: NGS-17, NGS17, TAP-associated protein, TAP-binding protein, TAPA, TPN, TPSN

Molecular Weight: TAPBP: 30 kDa

Gene ID: 6892

NCBI Accession: NM_172208