TMEM67 antibody

Catalog No. ABIN1112910

Product Details anti-TMEM67 Antibody

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM67 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: affinity purified

Isotype: IgG

Application Details

Application Notes: WB (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TMEM67

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Alternative Name: Meckelin (TMEM67 Products)

Synonyms: JBTS6 antibody, MECKELIN antibody, MKS3 antibody, NPHP11 antibody, TNEM67 antibody, 5330408M12Rik antibody, B230117O07 antibody, b2b1163.1Clo antibody, b2b1291.1Clo antibody, Wpk antibody, transmembrane protein 67 antibody, TMEM67 antibody, tmem67 antibody, Tmem67 antibody

Background: Meckelin, also called Transmembrane protein 67 (TMEM67), which encoded by the TMEM67 gene, is a 995-amino acid protein, localizes to the primary cilium and to the plasma membrane. Using in situ hybridization with human embryos, Dawe et al. (2007) found that meckelin was expressed in kidney, liver, retina, hindbrain, developing sphenoid bone, and the brain midline. The lack of this protein will cause Meckel syndrome type 3 (MKS3) , nephronophthisis and Joubert syndrome type 6 (JBTS6).