TNFRSF13C antibody

Catalog No. ABIN1169048

There are 2+ publications for this product available. The Rat Monoclonal anti-TNFRSF13C antibody is suitable to detect TNFRSF13C in samples from Mouse. It has been validated for FACS and Func.

Quick Overview for TNFRSF13C antibody (ABIN1169048)

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TNFRSF13C antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 9B9

Product Details anti-TNFRSF13C Antibody

Specificity: Recognizes mouse BAFF-R.

Cross-Reactivity: Mouse (Murine)

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95 % (SDS-PAGE)

Endotoxin Level: <0.01EU/μg purified protein (LAL test, Lonza).

Immunogen: Y3 cells transfected with mouse BAFF-R.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-TNFRSF13C antibody (ABIN1169048)

Tussiwand, Rauch, Flück, Rolink: "BAFF-R expression correlates with positive selection of immature B cells." in: European journal of immunology, Vol. 42, Issue 1, pp. 206-16, (2012) (PubMed).

Rauch, Tussiwand, Bosco, Rolink: "Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells." in: PLoS ONE, Vol. 4, Issue 5, pp. e5456, (2009) (PubMed).

Target Details for TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Alternative Name: BAFF-R

Background: Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.

UniProt: Q9D8D0

Pathways: NF-kappaB Signaling