ITGA2 antibody (Biotin)

Catalog No. ABIN118697

Product Details anti-ITGA2 Antibody (Biotin)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises the integrin alpha 2 subunit. Clone AK7 inhibits cell attachment to collagen.

Purification: Affinity Chromatography on Protein G.

Immunogen: Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.

Clone: AK7

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: CD49b / ITGA2 (ITGA2 Products)

Synonyms: BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody

Background: CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2

Gene ID: 3673

NCBI Accession: NP_002194

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex