CD25 antibody (Biotin)

Catalog No. ABIN133332

Product Details anti-CD25 Antibody (Biotin)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: Rat CD25 (IL-2R)

Immunogen: T blasts from a mixed lymphocyte reaction between purified CD4 positive T cells and irradiated spleens. . Donor: BALB/c spleen

Clone: OX-39

Isotype: IgG1

Application Details

Application Notes: This clone is reported to work with frozen and paraffin sections (3).

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/ml

Buffer: Biotin conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from bioreactor supernatant)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25 (IL-2R) (IL2RA Products)

Synonyms: CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody

Background: Anti-rat Interleukin-2 receptor monoclonal antibody recognizes the smaller (alpha subunit) 55kD chain of the IL-2 receptor found on activated rat T cells, thymic dendritic cells but not resting lymphocytes (1). ABIN133332binds to the rat interleukin-2 receptor and has proven to be an important marker for activated T cells (2). This clone is reported to work with frozen and paraffin sections (3).

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation