L-Selectin antibody (FITC)
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- Target See all L-Selectin (SELL) Antibodies
- L-Selectin (SELL) (Selectin L (SELL))
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This L-Selectin antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS), ELISA
- Specificity
- Rat Leukocyte Common Antigen (L-selectin)
- Purification
- Ion exchange
- Immunogen
- Recombinant rat L-selectin . Fusion Partner: NSI/1 . Donor: BALB/c Spleen
- Clone
- OX-85
- Isotype
- IgG1
- Top Product
- Discover our top product SELL Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 1.0 g /10 cells
- Storage
- 4 °C
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Alternative Name
- CD62L (SELL Products)
- Synonyms
- CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
- Background
- FITC anti-rat CD62L monoclonal antibody recognizes rat leukocyte selectin (L-selectin). CD62L is expressed constitutively on leukocytes and is expressed by a subset of thymocytes predominantly single positive CD4 or CD8 cells and a majority of lymph node cells in rats. CD62L binds well to O-glycans present on certain glycoforms of the mucins GlyCAM-1, CD34 and MAdCAM-1. CD62L is reported to be capable of reported to be capable of capable of transducing signals when cross-linked and has been shown to stimulate -integrin-mediated adhesion when bound to soluble GlyCAM-1. [1] L-selectin expressing CD4 CD8 thymocytes were shown through adoptive transfer to protect rats from insulin-dependent diabetes. CD4 CD8 thymocytes must mature to the stage of L-selectin expression before they can mediate normal T cell function. [2] Sensitive detection systems may be required on some tissues as expression of rat CD62L is weak.
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