CD80 antibody
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- Target See all CD80 Antibodies
- CD80
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD80 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Mouse CD80 (B7-1)
- Purification
- Purified
- Isotype
- IgG2a
- Top Product
- Discover our top product CD80 Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/ml
- Buffer
- Purified Ig buffered in PBS, 0.1% NaN and EIA grade BSA to bring total protein concentration to 4-5 mg/ml.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD80
- Alternative Name
- CD80 (CD80 Products)
- Synonyms
- B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
- Background
- ABIN134038reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell co- stimulation via interactions with CD28 and CTLA-4. CD80 is constitutively ex- pressed on dendritic cells, monocytes, and peritoneal macrophages and it is in- ducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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