CPT1C antibody (AA 121-170) (Alexa Fluor 488)
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- Target See all CPT1C Antibodies
- CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
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Binding Specificity
- AA 121-170
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CPT1C antibody is conjugated to Alexa Fluor 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Cpt1c
- Isotype
- IgG
- Top Product
- Discover our top product CPT1C Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
- Alternative Name
- Cpt1c (CPT1C Products)
- Synonyms
- 6530437J22Rik antibody, 9630004I06Rik antibody, CATL1 antibody, CPT1-B antibody, CPT1P antibody, CPTI-B antibody, CPTIC antibody, CPT IC antibody, carnitine palmitoyltransferase 1c antibody, carnitine palmitoyltransferase 1C antibody, Cpt1c antibody, CPT1C antibody
- Background
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Synonyms: CPT1-C, Carnitine acyltransferase like protein 1, Carnitine acyltransferase like protein1, Carnitine O palmitoyltransferase I, brain isoform, Carnitine palmitoyltransferase 1, brain, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase I related C, Carnitine palmitoyltransferase1C, CAT L1, CATL 1, CATL1, CPT 1 like pseudogene, Cpt 1c, CPT 1P, CPT I C, Cpt1 c, CPT1 like pseudogene, CPT1P , CPTIC.CPT1C_HUMAN
Background: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
- Gene ID
- 126129
- Pathways
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
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