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Syntaxin 6 antibody (AA 161-255) (HRP)

STX6 Reactivity: Human ELISA, WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1408118
  • Target See all Syntaxin 6 (STX6) Antibodies
    Syntaxin 6 (STX6)
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 161-255
    Reactivity
    • 61
    • 18
    • 17
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 6
    • 2
    • 2
    Rabbit
    Clonality
    • 66
    • 6
    Polyclonal
    Conjugate
    • 27
    • 8
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Syntaxin 6 antibody is conjugated to HRP
    Application
    • 51
    • 33
    • 13
    • 13
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Syntaxin 6
    Isotype
    IgG
    Top Product
    Discover our top product STX6 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Syntaxin 6 (STX6)
    Alternative Name
    Syntaxin 6 (STX6 Products)
    Synonyms
    CG7736 antibody, CT23545 antibody, Dm Syx6 antibody, DmSyx6 antibody, Dmel\\CG7736 antibody, SYN6 antibody, SYX6/10 antibody, Syx antibody, MGC78971 antibody, MGC132090 antibody, STX6 antibody, fb51b08 antibody, wu:fb51b08 antibody, zgc:110658 antibody, si:dkey-121a11.2 antibody, LOC734102 antibody, Syx6 antibody, Bmsyx6 antibody, Syntaxin-6 antibody, 2310039E05Rik antibody, 2410005I16Rik antibody, AA437559 antibody, AI415714 antibody, AI845861 antibody, Syntaxin 6 antibody, syntaxin 6 L homeolog antibody, syntaxin 6 antibody, Syx6 antibody, stx6.L antibody, STX6 antibody, stx6 antibody, Stx6 antibody
    Background

    Synonyms: STX 6, STX6, STX-6, STX6_HUMAN, Syntaxin-6, Syntaxin6.

    Background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.

    Pathways
    Synaptic Vesicle Exocytosis
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