GLYT1 antibody (AA 209-285) (Cy5.5)
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- Target See all GLYT1 Antibodies
- GLYT1 (Glycine Transporter 1 (GLYT1))
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Binding Specificity
- AA 209-285
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLYT1 antibody is conjugated to Cy5.5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9
- Isotype
- IgG
- Top Product
- Discover our top product GLYT1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GLYT1 (Glycine Transporter 1 (GLYT1))
- Alternative Name
- Glyt1/SLC6A9 (GLYT1 Products)
- Synonyms
- GLYT1 antibody, Glyt-1 antibody, Glyt1 antibody, GLYT-1 antibody, GLYT-1b antibody, glyt1 antibody, slc6a9 antibody, glyT-1 antibody, glyT1 antibody, solute carrier family 6 member 9 antibody, solute carrier family 6 (neurotransmitter transporter, glycine), member 9 antibody, glycine transporter 1 antibody, SLC6A9 antibody, Slc6a9 antibody, glyt1 antibody, slc6a9 antibody
- Background
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Synonyms: glycine transporter 1, Glyt 1, GlyT-1 antibodyGlyT1, SC6A9_HUMAN, SLC6A9, sodium and chloride dependent glycine transporter 1, Sodium- and chloride-dependent glycine transporter 1, Solute carrier family 6 member 9.
Background: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
- Gene ID
- 6536
- UniProt
- P48067
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