MKNK1 antibody (pThr250)

Catalog No. ABIN1450437

Product Details anti-MKNK1 Antibody

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Binding Specificity: AA 216-265, pThr250

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

MNK1 (Phospho-Thr250) Antibody detects endogenous levels of MNK1 only when phosphorylated at Thr250.

PhosphorylationH:T250, M:T209, R:T197

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human MNK1 around the phosphorylation site of Thr250.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MNK1 (MKNK1 Products)

Synonyms: MNK1 antibody, MKNK1 antibody, zgc:171912 antibody, 2410048M24Rik antibody, Mnk1 antibody, MAPK signal-integrating kinase 1 antibody, mknk1 antibody, mnk1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase-interacting serine/threonine kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 S homeolog antibody, MKNK1 antibody, mknk1 antibody, Mknk1 antibody, mknk1.S antibody

Background:

Synonyms: kinase Mnk1, Map kinase interacting kinase, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine kinase 1, MKNK1

NCBI Gene Symbol: MKNK1

Molecular Weight: 51 kDa

Gene ID: 8569

OMIM: 606724

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor