Insulin Receptor antibody (pTyr972)

Catalog No. ABIN1495716

Product Details anti-Insulin Receptor Antibody

Target: Insulin Receptor (INSR)

Binding Specificity: pTyr972

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human and mouse IR. Rat (100 % homologous) IR has not been tested, but is expected to react. IGF1R [pY950] (75 % homologous) has been shown to cross-react in some cell systems

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ulrich, et al.). The sequence is conserved in mouse and rat.

Type of Immunogen: Synthetic phospho-peptide

Application Details

Application Notes: Approved: WB (1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Dulbecco's PBS (without Mg2+, Ca2+),  pH 7.3 (+/- 0.1), 50 % glycerol, 1.0 mg/mL BSA (IgG, protease free) as a carrier.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: Insulin Receptor (INSR Products)

Synonyms: CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody

Background: Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase

Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

Gene ID: 3643

UniProt: P06213

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity